Bioinformatics News Aug 2009: bioinformatics, genomics, proteomics, microarray, etc.

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Addario Lung Cancer Medical Institute Announces Diagnostic Screening and Clinical Research Collaborations With ...
SAN FRANCISCO, July 31 /PRNewswire-USNewswire/ -- The Addario Lung Cancer Medical Institute (ALCMI) today announced the execution of a letter of intent (LOI) to collaborate with Response Genetics, Inc. (Sat, 01 Aug 2009 03:22:40 GMT)

TGen gets $1 mil to study melanoma
The Melanoma Research Alliance has awarded $1 million to a TGen-led research team to uncover new genetic clues to skin cancer. (Sat, 01 Aug 2009 05:13:38 GMT)

Experts urge panel to deepen forensic understanding
WASHINGTON -- A panel of experts convened for a second day Friday to examine the scientific process employed by the FBI to identify the anthrax used in the deadly 2001 mailings (Sat, 01 Aug 2009 06:02:54 GMT)

Algebra Adds Value To Mathematical Biology Education
As mathematics continues to become an increasingly important component in undergraduate biology programs, a more comprehensive understanding of the use of algebraic models is needed by the next generation of biologists to facilitate new advances in the life sciences, according to researchers at Sweet Briar College and the Virginia Bioinformatics Institute (VBI) at Virginia Tech. (Sat, 01 Aug 2009 10:17:26 GMT)

Merck to buy genomic analysis services for 5 yrs from Covance for $145 mn
Covance has entered into a definitive agreement with Merck & Co, Inc relating to the supply of genomic analysis services. Under the terms of the agreement Merck has committed to a five-year $145 million contract to purchase genomic analysis services from Covance. (Sat, 01 Aug 2009 10:44:39 GMT)

Scientists Mesh Array, Interaction Data to Form Dynamic Picture of Protein Complex
Scientists at the European Molecular Biological Laboratory and the Technical University of Denmark have combined microarray data with protein-protein interaction data to come up with a novel way of observing how protein complexes form dynamically, with a few elements of the complexes corresponding temporally to the cell cycle. (Sat, 01 Aug 2009 20:15:33 GMT)

DiaGenic Taps Opaldia to Sell Breast Cancer, Alzheimer’s Diagnostics in UK
Norwegian life sciences company DiaGenic announced last week that it has hired British genetic-testing start-up Opaldia to sell its genetic tests in the UK. (Sat, 01 Aug 2009 20:15:53 GMT)

TECH: Taming Twitter: Pros give their tips
The microblogging service Twitter has received a lot of mockery, perhaps more than any other social networking phenomenon. Critics deride it as frivolous, a time-waster, a narcissistic fixation, a fad like CB radio in the 1970s, and a distraction from work. (Sun, 02 Aug 2009 00:25:02 GMT)

On the job at TGen
Student interns got a real dose of what it takes to work in a research lab this summer at the Translational Genomics Research Institute in Phoenix. (Sun, 02 Aug 2009 00:50:57 GMT)

Wisconsinites commute by jet to high-flying careers
When Milwaukee mathematician Peter Tonellato took a job in Boston, he added 1,042 miles to his commute. Tonellato is among a small cadre of Wisconsinites taking to the air regularly and enthusiastically to travel to high-end jobs in far-flung places. (Sun, 02 Aug 2009 05:52:56 GMT)

Shimadzu and Proteome Systems Expand North American Marketing Alliance
NEW YORK, March 2 (GenomeWeb News) - Shimadzu Scientific Instruments and Proteome Systems have expanded a broad alliance that they began in 2000, the companies said today. (Sun, 02 Aug 2009 20:15:33 GMT)

Knome Selects Sterling Communications as Agency of Record
Sterling Communications Inc., an independent, full-service, high-tech public relations agency, today announced the addition of Knome to its client portfolio of industry-leading technology companies. (Mon, 03 Aug 2009 09:30:00 GMT)

Boston University School of Medicine and Bruker Establish a Collaborative Effort in Glycomics and Advanced FTMS ...
BILLERICA, Mass.----Bruker Daltonics announced today that it has established a collaboration with the Mass Spectrometry Resource laboratory of Professor Catherine Costello at the Boston University School of Medicine . (Mon, 03 Aug 2009 11:00:00 GMT)

Risk of Pancreatic Cancer Linked to Variation in Gene that Determines Blood Type
Common variants of the gene that determines human blood type are associated with an increased risk of pancreatic cancer, according to a study by scientists at the National Cancer Institute (NCI), part of the National Institutes of Health, and colleagues from many universities and research institutions. (Mon, 03 Aug 2009 12:24:28 GMT)

International Milk Genomics & Human Health Symposium Speaker Program Announced
The speaker program for the 6th International Symposium on Milk Genomics & Human Health has been released. The three-day event will be held September 28-29, 2009 at the Mercure Paris Porte de Versailles Expo Hotel in Paris, France. The agenda for the 6th annual meeting includes presentations on the Lactation Genome, Mammary Development and Insights Into Milk and Immunity. (Mon, 03 Aug 2009 13:00:00 GMT)

TGen-led team is 1 of 7 selected for $1 million skin-cancer grants
( The Translational Genomics Research Institute ) An international scientific team led by the Translational Genomics Research Institute has received a $1 million grant to study skin cancer from the Melanoma Research Alliance. The grant was made to a team led by Dr. Jeffrey Trent, TGen's President and Research Director, who is the team lead among the principal investigators in the two-year study: ... (Mon, 03 Aug 2009 13:01:13 GMT)

Your Genome: There's an App for That
Don't look now, but we may be about to enter the genome-based economy. Soon, having a personalized analysis of your human genomes will be as commonplace as taking an IQ test in school. You could carry a specially-tuned smartphone able to scan the UPC of any clothing or food substance you buy. (Mon, 03 Aug 2009 13:05:10 GMT)

Clark Atlanta, Ga. Tech team up on cancer center
Atlanta will soon get a high-tech cancer research institute aimed at beating prostate cancer. (DNDN) (Mon, 03 Aug 2009 14:33:04 GMT)

BU Mass Spec Resource to Collaborate With Bruker
NEW YORK (GenomeWeb News) – Bruker Daltonics and Boston University's Mass Spectrometry Resource plan to collaborate to apply high performance ion trap mass spectrometry and Fourier transform mass spec to glycomics and proteomics research, Bruker announced today. (Mon, 03 Aug 2009 14:45:43 GMT)

Biotech Hot in July Driven by Positive Drug Data and Acquisitions
Biotech was "hot" in July driven by drug data, positive drug sales/earnings and partnering and M&A deals. As a result, the Burrill Biotech Select Index posted a solid monthly gain of 6.5 percent, mirroring the Dow and Nasdaq, which closed the month up 8.6 percent and 7.8 percent respectively marking their best performance for a July in years. (Mon, 03 Aug 2009 16:06:00 GMT)

Gene Atlas Project Looks To Identify Gene Function
As part of our mission to benefit farmers and ranchers, the Noble Foundation works to improve vital grasses and legumes through traditional breeding and scientific research. (Mon, 03 Aug 2009 16:49:21 GMT)

Funding Update
Funds development of tools to identify previously unknown, putative genes in metagenomic sequence data. According to the abstract, Brian Palenik, the principal investigator, is developing tools for the analysis of metaproteomes using metagenomics data obtained from the same site. (Mon, 03 Aug 2009 17:15:33 GMT)

New Tool Could Help With Early Detection Of Deadly Pancreatic Cancer
A new diagnostic tool developed by Van Andel Research Institute (VARI) scientists has shown promising results when used with patients of pancreatic cancer, one of the deadliest forms of cancer due to the difficulty of diagnosing it in its early stages. (Mon, 03 Aug 2009 17:23:26 GMT)

New tool may help with early detection of deadly pancreatic cancer
( Van Andel Research Institute ) A new diagnostic tool developed by Van Andel Research Institute scientists has shown promising results when used with patients of pancreatic cancer, one of the deadliest forms of cancer due to the difficulty of diagnosing it in its early stages. The method, which studies carbohydrate structures in the bloodstream, could lead to the development of blood tests that ... (Mon, 03 Aug 2009 17:46:56 GMT)

New tool may help with early detection of deadly pancreatic cancer
A new diagnostic tool developed by Van Andel Research Institute (VARI) scientists has shown promising results when used with patients of pancreatic cancer, one of the deadliest forms of cancer due to the difficulty of diagnosing it in its early stages. The method, which studies carbohydrate structures in the bloodstream, could lead to the development of blood tests that can detect cancer more ... (Mon, 03 Aug 2009 18:15:53 GMT)

Turner BioSystems Combines with Promega to Expand Integrated Systems Offerings
MADISON, Wis.----Promega Corporation announces the recent purchase of Turner BioSystems Inc. to grow their mutual interest in offering high quality integrated systems to life scientists in research, drug discovery and clinical diagnostics. (Mon, 03 Aug 2009 19:00:00 GMT)

Protagen Completes $5.3M Funding Round
NEW YORK (GenomeWeb News) – Protagen has received €3.7 million ($5.3 million) in funding from existing institutional European investors, the company said today. (Mon, 03 Aug 2009 19:15:33 GMT)

TGen, Yale Win $2M for Melanoma Genomics Studies
NEW YORK (GenomeWeb News) – As part of a $7 million round of funding for a range of molecular and cellular studies of melanoma, the Melanoma Research Alliance has granted $2 million for genomics studies through awards to the Translational Genomics Research Institute and to Yale University. (Mon, 03 Aug 2009 19:15:43 GMT)

Please Step Away from the Car
There are few things that GTO enjoys more than a good rant. Check out this post from Mike the Mad Biologist arguing that the human microbiome initiative "is being driven by the wrong group of scientists." (Mon, 03 Aug 2009 21:15:33 GMT)

Power-hungry supercomputers going green
Speed and power have long been the most important criteria when judging a supercomputer's worth as a number-crunching lab workhorse, but energy efficiency is fast catching up. The greenest supercomputers are those that can process the most scientific calculations per second while drawing the least power. [More] (Mon, 03 Aug 2009 21:45:27 GMT)

Will you inherit your mother's face?
Bazaar investigates what's behind the aging process and how the new high-tech products can help you both look younger. (Mon, 03 Aug 2009 23:28:52 GMT)

Labcyte Echo Acoustic Liquid Handler an Essential Component of Pharmaceutical High-Throughput Screening
SUNNYVALE, Calif.----The most recent edition of the Journal of Biomolecular Screening, the world's leading peer-reviewed publication on drug discovery sciences, focused on the significant advances made recently in the field of compound management. (Tue, 04 Aug 2009 05:00:00 GMT)

Recession-proof companies Part I: Galapagos
Galapagos CEO Onno van de Stolpe talks to Pharm Exec Europe about his 10-year run at the head of the company, a highly successful tenure that shows no sign of slowing down. (Tue, 04 Aug 2009 05:09:49 GMT)

Risk Of Pancreatic Cancer Linked To Variation In Gene That Determines Blood Type
Common variants of the gene that determines human blood type are associated with an increased risk of pancreatic cancer, according to a study by scientists at the National Cancer Institute (NCI), part of the National Institutes of Health, and colleagues from many universities and research institutions. (Tue, 04 Aug 2009 05:15:02 GMT)

Being Exclusive
The latest version of the US health bill includes a provision about generic biotech drugs . The version passed by the House Energy and Commerce Committee gives biotech drugs 12-year exclusivity period, reports the Wall Street Journal Health Blog. The chair of the committee, Henry Waxman, earlier this year called for a five-year period of exclusivity. (Tue, 04 Aug 2009 05:15:52 GMT)

Fuel and Oil: Related News
8/4/2009 - Speculation Blamed for Petroleum Run-up Speculation in the petroleum futures market was a major contributor to the rise in oil prices during 2008, according to Gary Gensler, chair of the Commodity Futures Trading Commission.... (Tue, 04 Aug 2009 07:09:59 GMT)

New tool can detect pancreatic cancer more effectively than current tests
Washington, Aug 4 : Van Andel Research Institute (VARI) scientists have developed a new tool that can detect pancreatic cancer much more effectively than current tests. (Tue, 04 Aug 2009 09:41:41 GMT)

Risk of Pancreatic Cancer Linked to Variation in Gene That Determines Blood Type
Common variants of the gene that determines human blood type are associated with an increased risk of pancreatic cancer, according to a study by scientists at the National Cancer Institute (NCI), part of the National Institutes of Health, and colleagues from many universities and research institutions. (Tue, 04 Aug 2009 10:02:44 GMT)

Aug 04th
A major international player is the latest in a growing line of pharmaceutical giants to take technology from exciting young Cambridge company Horizon Discovery. (Tue, 04 Aug 2009 10:05:32 GMT)

Photos: Advanced Electron Beams Raises $14.2 Million From GE, Flagship Ventures & Others for Market Penetration and ...
Advanced Electron Beams , whose compact electron beam technology helps traditional manufacturers become more environmentally sustainable while improving profitability, and GE Energy Financial Services, a unit of GE announced today the close of a $14.2 million Series C financing, bringing AEB's total amount raised to more than $50 million since October 2005. (Tue, 04 Aug 2009 12:00:00 GMT)

Agricultural research key to food security
( TWAS ) Boosting agricultural research in the developing world is the key to ensuring food security for the world's poorest, says Adel el-Beltagy, chair of the Global Form on Agricultural Research. (Tue, 04 Aug 2009 13:05:16 GMT)

New Tool May Help With Early Detection Of Deadly Pancreatic Cancer
A new diagnostic tool has shown promising results when used with patients of pancreatic cancer, one of the deadliest forms of cancer due to the difficulty of diagnosing it in its early stages. The method, which studies carbohydrate structures in the bloodstream, could lead to the development of blood tests that can detect cancer more effectively. (Tue, 04 Aug 2009 13:21:58 GMT)

Janssen to Use Horizon Cell Lines in Research
NEW YORK (GenomeWeb News) – Horizon Discovery announced on its website today that it has inked a collaborative agreement with Janssen Pharmaceutica division Ortho Biotech Oncology Research & Development. (Tue, 04 Aug 2009 13:45:33 GMT)

U.S. Patent to be Granted for Aushon Microarray Printing Technology
BILLERICA, Mass.----Aushon BioSystems, Inc., a leading provider of advanced microarray instrumentation and laboratory services for biomarker discovery, development and analysis has announced that its request for a U.S. patent covering its advanced microarray printing technology has been approved. (Tue, 04 Aug 2009 14:00:00 GMT)

LabCorp Completes Monogram Offer; Merger Will be Completed Today
NEW YORK (GenomeWeb News) – Laboratory Corporation of America today said that its tender offer for all outstanding shares of common stock of Monogram Biosciences expired at midnight last night, and the firm expects to complete its $107 million purchase at the close of business today. (Tue, 04 Aug 2009 14:00:33 GMT)

Satoris to Distribute RBM's Biomarker Panel for Neuro Research
NEW YORK (GenomeWeb News) – Molecular diagnostics firm Satoris today said that it has been appointed global distributor for Rules-Based Medicine's DiscoveryMAP panel for neurology research. (Tue, 04 Aug 2009 14:00:43 GMT)

NIDA Plans to Fund Epigenomics of HIV
NEW YORK (GenomeWeb News) – The National Institute on Drug Abuse plans to fund research that will use epigenomics approaches to study HIV and how it is linked to substance abuse, the National Institutes of Health said in a notice posted on its website. (Tue, 04 Aug 2009 14:00:53 GMT)

New Tool May Help With Early Detection Of Deadly Pancreatic Cancer
A new diagnostic tool developed by Van Andel Research Institute (VARI) scientists has shown promising results when used with patients of pancreatic cancer, one of the deadliest forms of cancer due to the difficulty of diagnosing it in its early stages. (Tue, 04 Aug 2009 14:18:57 GMT)

You Always Remember Your First
Jonathan Eisen shares the embarrassing story of his first conference talk at his blog The Tree of Life. Not only did he barely sleep the night before (his room lacked an alarm clock and his talk was an early one), but just before his talk, he sat in a puddle of water spilled from a pitcher. (Tue, 04 Aug 2009 16:00:46 GMT)

Congrats to All
Among the 16 new US Medal of Freedom awardees are three academics , points out the Chronicle of Higher Education . They are: the University of Chicago's Janet Rowley, who discovered the role chromosomal translocations play in leukemia and other cancers; Florida International University's Pedro Greer, Jr., for his work to provide medical care to Miami's poor; and the University of Cambridge's ... (Tue, 04 Aug 2009 16:00:52 GMT)

What's Your Favorite?
Nature Methods is now taking nominations and votes for the 2009 Method of the Year. Head on over here to submit your favorite method or class of methods for consideration. (Tue, 04 Aug 2009 16:00:58 GMT)

Agricultural Research Is Key To Food Security
Boosting agricultural research in the developing world is the key to ensuring food security for the world's poorest, says Adel el-Beltagy, Chair of the Global Form on Agricultural Research (GFAR), writing in the latest issue of the TWAS Newsletter, published last week.With nearly a billion people suffering from chronic hunger, global food security remains a major concern, despite being a key ... (Tue, 04 Aug 2009 16:24:48 GMT)

Stellar Pharmaceuticals to Host Second Quarter 2009 Earnings Conference Call
- Company to hold Conference Call Wednesday, August 5 at 11:00 am ET - Stellar has three consecutive quarters showing profit - Q2 2009 revenues increase 65.8% to $1.1 million (Tue, 04 Aug 2009 16:25:50 GMT)

CapitalBio, VigeneTech to Co-market Instruments, Analysis Software as Integrated Array System
Beijing-based CapitalBio and Carlisle, Mass.-based VigeneTech have partnered to sell CapitalBio's scanners together with VigeneTech's analysis software as an integrated microarray platform, the companies said last week. (Tue, 04 Aug 2009 16:45:33 GMT)

At Least 34 Research Jobs at Stanford Medical School from Stimulus Funds
STANFORD, Calif.----Sean Mackey, MD, PhD, has been studying the roots of pain in the brain, applying last year for a grant from the National Institutes of Health to continue his imaging studies in the field. (Tue, 04 Aug 2009 16:57:00 GMT)

Funding Update
Using rice as a model and approaches that include chromatin immunoprecipitation and DNA sequencing, this project will reveal the location of epigenetic marks, such as cytosine DNA methylation and histone modifications, associated with centromeric chromatin. (Tue, 04 Aug 2009 17:15:34 GMT)

Q&A: MPI's Margret Hoehe on MHC Haplotype Sequencing by SOLiD
Margret Hoehe leads the Genetic Variation, Haplotypes and Genetics of Complex Disease group in the department of Vertebrate Genomics at the Max Planck Institute for Molecular Genetics in Berlin. (Tue, 04 Aug 2009 17:45:54 GMT)

Note to Subscribers
In Sequence will be on hiatus August 5 through August 11. The next issue of the newsletter will be sent to subscribers on August 18. (Tue, 04 Aug 2009 18:00:35 GMT)

IP Roundup
Northwestern University has received US Patent No. 7,569,340, "Nanoarrays of single-virus particles, methods, and instrumentation for the fabrication and use thereof." (Tue, 04 Aug 2009 19:15:33 GMT)

People in the News
PerkinElmer has named Lapo Paladini to the new position of chief marketing officer and to serve as senior vice president. (Tue, 04 Aug 2009 19:15:43 GMT)

Clark Atlanta Starting Cancer Genomics Center with GT
NEW YORK (GenomeWeb News) – Clark Atlanta University tomorrow will publicly launch its Collaborative Cancer Genomics Center, a collaboration with the Georgia Institute of Technology and St. Joseph's Hospital in Atlanta that was funded with federal and regional public and private funds. (Tue, 04 Aug 2009 19:45:53 GMT)

African village dogs are genetically much more diverse than modern breeds
( Cornell University ) African village dogs are not a mixture of modern breeds but have directly descended from an ancestral pool of indigenous dogs, according to a Cornell-led genetic analysis of hundreds of semi-feral African village dogs. (Tue, 04 Aug 2009 19:47:58 GMT)

Celera Presents Data Replicating Its Immunodiagnostic Assay to Detect Lung Cancer from Blood Serum
ALAMEDA, Calif.----Celera Corporation today announced the presentation of data replicating its novel mass spectrometry-based approach to identify and validate circulating protein biomarkers that detect non-small cell lung cancer in an independent cohort of individuals with lung cancer. (Tue, 04 Aug 2009 20:00:00 GMT)

High-tech called key to healthcare savings
SAN JOSE, Calif., Aug. 4 (UPI) -- Dozens of U.S. entrepreneurs see new technologies as a way of transforming healthcare -- and saving money at the same time, The Wall Street Journal reports. (Tue, 04 Aug 2009 21:05:28 GMT)

They Must've Narrowly Beaten Out Bush and Cheney
US News & World Report has a special feature on 18 of America's top leaders , and GTO was pleased to see that a number of scientists made the list. These include Harold Varmus , now at Memorial Sloan-Kettering Cancer Center (the profile was written by Bernadine Healy), Shirley Tilghman at Princeton, and William Foege at the Bill and Melinda Gates Foundation. (Tue, 04 Aug 2009 22:30:33 GMT)

High-tech called key to healthcare savings
Dozens of U.S. entrepreneurs see new technologies as a way of transforming healthcare -- and saving money at the same time, The Wall Street Journal reports. Triage Wireless Inc. (Tue, 04 Aug 2009 23:09:51 GMT)

Moonbots Challenges Parent-Child Teams To Conduct Google Lunar X Prize Missions With Lego Robots
The X PRIZE Foundation, Google Inc., LEGO Systems, National Instruments, and Wired's GeekDad will announce "MoonBots: A Google Lunar X PRIZE LEGO(R) MINDSTORMS(R) Challenge" today at National Instruments NIWeek 2009. (Tue, 04 Aug 2009 23:26:03 GMT)

Finalist for UCR post champions diversity
Dr. Jeanette Mladenovic, a finalist to be dean of the proposed UC Riverside medical school, stressed during a campus forum Tuesday that the school needs to reflect the Inland area's diversity. (Wed, 05 Aug 2009 01:57:01 GMT)

Fuel and Oil: Related News
8/5/2009 - Oregon B2 Requirement Effective Wednesday Oregon will start enforcing a 2 percent biodiesel requirement today, making it the third state mandating the fuel... (Wed, 05 Aug 2009 07:09:29 GMT)

Agricultural research key to food security for world’s poorest
Washington, August 5 : A new research paper has determined that boosting agricultural research in the developing world is the key to ensuring food security for the world’s poorest. (Wed, 05 Aug 2009 09:16:48 GMT)

GenVault's GenSolve(TM) Reagents Enable State-of-the-Art Genomic Analysis of Dried Blood Spots
GenVault Corporation is pleased to report that their DNA recovery product, GenSolve, is enabling independent groups, from diverse research areas, to recover DNA from Guthrie cards and FTA paper for microarray based genomic analysis and Illumina iSelect based genotyping. (Wed, 05 Aug 2009 12:57:00 GMT)

The NIAID-Supported Pathogen Functional Genomics Resource Center at the J. Craig Venter Institute Offers New ...
SANTA CLARA, Calif. & ROCKVILLE, Md.----Affymetrix, Inc. and the National Institute of Allergy and Infectious Diseases -supported Pathogen Functional Genomics Resource Center at the J. (Wed, 05 Aug 2009 13:00:00 GMT)

Papers of Note
As the head of the Vertebrate Genomics Group at the European Bioinformatics Institute and a co-leader of the data flow group for the 1,000 Genomes Project, Paul Flicek is intimately familiar with the ongoing battle to make sense out of the endless stream of next-gen sequencing data. (Wed, 05 Aug 2009 13:30:33 GMT)

Obama administration announces more than $327 million in Recovery Act funding for science research
( DOE/US Department of Energy ) US Department of Energy Secretary Steven Chu announced today that more than $327 million in new funding from the American Recovery and Reinvestment Act will go toward scientific research, instrumentation and laboratory infrastructure projects. Ten of DOE's national laboratories in six states will be receiving funds, along with researchers at institutions of higher ... (Wed, 05 Aug 2009 14:13:52 GMT)

LifeScienceFest 2009 Brings Leading Medical Technology/Life Science Investors and Innovations Together in Silicon Valley
MENLO PARK, Calif.----Top industry investors, innovators and executives will come together on September 9 at Investorfest Media's LifeScienceFest in Menlo Park, CA. The full-day conference will bring together leading investors with prior history and active focus on the medical and life sciences sector to hear directly from a broad range of entrepreneurs delivering medical devices, diagnostics, ... (Wed, 05 Aug 2009 14:30:00 GMT)

Persistent Systems Announces Industry's First Independent Device Driver Portal
DriverCentral.net Dedicated to Device Drivers for Analytical Instruments (Wed, 05 Aug 2009 14:40:53 GMT)

CapitalBio Corporation and VigeneTech Inc. Have Announced the Launch of a Fully Integrated Microarray Solution Platform
CapitalBio Corporation and VigeneTech Inc. have announced the launch of a fully integrated microarray solution platform. CapitalBio Corp., a developer and marketer of diagnostic biochips and advanced microarray instrument systems, in collaboration with VigeneTech, developers of novel image analysis, automation, and instrumentation software, now offers a platform that combines the superior ... (Wed, 05 Aug 2009 15:41:00 GMT)

Genvault's Gensolve(TM) Reagents Enable State-Of-The-Art Genomic Analysis
CARLSBAD, Calif., (Wed, 05 Aug 2009 15:48:45 GMT)

Urbana, Illinois, USA August 5, 2009
In a little over seven hours, University of Illinois weed scientist Patrick Tranel got more genetic information about waterhemp than in two years time in a lab. (Wed, 05 Aug 2009 16:04:08 GMT)

Understanding how weeds are resistant to herbicides
( University of Illinois at Urbana-Champaign ) In a little over seven hours, University of Illinois weed scientist Patrick Tranel got more genetic information about waterhemp than in two years time in a lab. The genetic information was obtained using pyrosequencing technology in the Keck Center at the U of I. The genetic sequence will allow scientists to study herbicide resistance in waterhemp. (Wed, 05 Aug 2009 16:04:51 GMT)

Ghostwriting Medicine
Twenty-six medical journals articles that supported the use of hormone replacement therapy in women were ghostwritten , reports the New York Times . The articles were initiated and paid for by Wyeth and did not disclose that connection. (Wed, 05 Aug 2009 16:15:36 GMT)

GI Bill and More Scientists
US President Obama says that the new GI Bill may lead to new scientists and engineers , reports Science Insider. (Wed, 05 Aug 2009 16:15:47 GMT)

A Whole Genome Mess
A whole-genome sequencing paper coming out in Genome Research used ABI's SOLiD platform to sequence the same person that the Illumina paper did, as Dan Koboldt points out . The SOLiD paper authors did not compare the sequences citing, in the comments to Koboldt's blog, the Illumina paper's lack of genotype information . And so in a guest post at Daniel MacArthur's blog, Luke Jostins embarks on ... (Wed, 05 Aug 2009 16:15:55 GMT)

Our Summer Camp Only Taught Us How to Use Lanyard
In China, 30 children between the ages of 3 and 12 are being tested " to identify genetic gifts and predict the future ," reports CNN. For $880, parents can sign their children up for summer camps at Chongqing Children's Palace and the genetic test conducted by Shanghai Biochip Corporation. (Wed, 05 Aug 2009 16:16:06 GMT)

PGI Visual Fortran 9.0 Adds Support for MPI Debugging on Windows HPC Server 2008 Clusters
PORTLAND, Ore., Aug. 5 /PRNewswire-FirstCall/ -- The Portland Group(R), a wholly-owned subsidiary of STMicroelectronics, today announced the general availability of PGI Visual Fortran(R) (PVF(R)) Release 9.0 for Windows workstations, servers and clusters. (Wed, 05 Aug 2009 16:23:16 GMT)

GenVault's GenSolve(TM) Reagents Enable State-of-the-Art Genomic Analysis of Dried Blood Spots
CARLSBAD, Calif., Aug. (Wed, 05 Aug 2009 16:24:57 GMT)

Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols
( Cold Spring Harbor Laboratory ) The August issue of Cold Spring Harbor Protocols features two methods for gene transfer in stem cells. (Wed, 05 Aug 2009 16:47:11 GMT)

This Week in Genome Research
In early online publication at Genome Research , a group of researchers led by McGill’s Tomi Pastinen and Elin Grundberg carried out a cell-type specific eQTL study of primary human osteoblasts, or bone cells, and combined it with publicly available GWAS data for bone mineral density. (Wed, 05 Aug 2009 18:00:34 GMT)

CapitalBio Corporation and VigeneTech Inc. Have Announced the Launch of a Fully Integrated Microarray Solution Platform
CARLISLE, Mass., Aug. 5 /PRNewswire/ -- CapitalBio Corporation and VigeneTech Inc. have announced the launch of a fully integrated microarray solution platform. (Wed, 05 Aug 2009 18:25:53 GMT)

NIH to Fund Bioinformatics Small Business Grants
NEW YORK (GenomeWeb News) – The National Institutes of Health will fund research into biomedical informatics and computational biology through three new programs, including two small business-focused grants. (Wed, 05 Aug 2009 19:30:53 GMT)

JDRF and GNF announce innovative diabetes drug discovery and development partnership
( Juvenile Diabetes Research Foundation International ) Juvenile Diabetes Research Foundation said today that it has entered into a novel collaborative research agreement with the Genomics Institute of the Novartis Research Foundation to create a diabetes drug discovery and development platform. The four-year program is one of the largest and most comprehensive collaborations in the 40 year ... (Wed, 05 Aug 2009 19:48:11 GMT)

Bruker, BUSM Mass Spec Center Collaborate on solariX Apps Development
In a bid to further build out applications for its mass spectrometers, in particular its recently launched high-end platforms, Bruker this week announced a collaboration with Catherine Costello, director of the Boston University School of Medicine Center for Biomedical Mass Spectrometry. (Wed, 05 Aug 2009 20:16:05 GMT)

Yes, U May Accurately Determine Protein Identification FDR with New Tool, Swiss Researchers Say
With the vast amount of data being generated by proteomics research, particularly shotgun proteomics, the ability to effectively determine the accuracy of protein identifications is gaining urgency. (Wed, 05 Aug 2009 20:30:43 GMT)

Canada August 5, 2009 Wheat breeders that used to search through binders of data can now make genetic comparisons with ...
(WGRF) Endowment Fund. Daryl Somers, Director of Applied Genomics at the Vineland Research and Innovation Centre in Vineland Station, Ontario, was working at Agriculture and Agri-Food Canada's Cereal Research Centre in Winnipeg when he led the project. (Wed, 05 Aug 2009 20:50:01 GMT)

Sex Hormone-Binding Globulin and Risk of Type 2 Diabetes in Women and Men
Background Circulating sex hormone-binding globulin levels are inversely associated with insulin resistance, but whether these levels can predict the risk of developing type 2 diabetes is uncertain. Methods We performed ... (Wed, 05 Aug 2009 21:47:25 GMT)

Browsing the Genome in Real-Time
Pierre Lindenbaum's blog, Yokofakun , points to Tim Yates's X:MAP , which is an interactive "genome browser that shows the location of individual exon probes with respect to their target genes, transcripts and exons." (Wed, 05 Aug 2009 22:17:07 GMT)

Yes, You Really Have to Study; No, You Don't Have to Get Out of Your Jammies
Here's a good excuse to brush up on your bioinformatics skills while lounging at home in your PJs: The University of Manchester will be hosting distance learning classes in bioinformatics this coming March, and applications are now being accepted . Courses include Bioinformatics for Systems Biology, Introduction to Microarray Data Analysis, The Science of Proteomics, and many more. (Wed, 05 Aug 2009 22:17:17 GMT)

Juvenile Diabetes Research Foundation, The Genomics Institute of the Novartis Research Foundation Announce Innovative ...
- Program Focuses on Expanding Pipeline of Drugs For People with Type 1 Diabetes - NEW YORK, Aug. (Wed, 05 Aug 2009 23:28:17 GMT)

Alpha Innotech Reports Second Quarter 2009 Results
SAN LEANDRO, Calif.----Alpha Innotech Corp. , a leading provider of bioanalytical systems for drug discovery and life science research, today reported financial results for their second quarter ending June 30, 2009. (Thu, 06 Aug 2009 00:54:00 GMT)

Celera Presents Data Replicating Its Immunodiagnostic Assay To Detect Lung Cancer From Blood Serum
Celera Corporation (NASDAQ:CRA) announced yesterday the presentation of data replicating its novel mass spectrometry-based approach to identify and validate circulating protein biomarkers that detect non-small cell lung cancer (NSCLC) in an independent cohort of individuals with lung cancer. This study was performed in collaboration with scientists at NYU Langone Medical Center, NY. (Thu, 06 Aug 2009 02:15:25 GMT)

Turner BioSystems Combines With Promega To Expand Integrated Systems Offerings
Promega Corporation announces the recent purchase of Turner BioSystems Inc. to grow their mutual interest in offering high quality integrated systems (optimized instrument with reagents) to life scientists in research, drug discovery and clinical diagnostics (Thu, 06 Aug 2009 05:05:20 GMT)

Labcyte Echo Acoustic Liquid Handler An Essential Component Of Pharmaceutical High-Throughput Screening
The most recent edition of the Journal of Biomolecular Screening, the world's leading peer-reviewed publication on drug discovery sciences, focused on the significant advances made recently in the field of compound management (Thu, 06 Aug 2009 05:05:40 GMT)

Juvenile Diabetes Research Foundation, The Genomics Institute Of The Novartis Research Foundation Announce Innovative ...
The Juvenile Diabetes Research Foundation said today that it has entered into a novel collaborative research agreement with the Genomics Institute of the Novartis Research Foundation (GNF) to create a diabetes drug discovery and development platform (Thu, 06 Aug 2009 05:06:10 GMT)

Expression Analysis launches new look
The url stays the same, but www.ExpressionAnalysis.com looks a lot different today. The redesigned website allows researchers and scientists to more easily navigate and locate the information and services they are looking for, in most cases in just one click. Additionally a revamped search tool enables users to find valuable information on a wide range of scientific topics. (Thu, 06 Aug 2009 05:57:26 GMT)

CapitalBio Corporation And VigeneTech Inc. Have Announced The Launch Of A Fully Integrated Microarray Solution Platform
CapitalBio Corporation and VigeneTech Inc. have announced the launch of a fully integrated microarray solution platform. CapitalBio Corp., a developer and marketer of diagnostic biochips and advanced microarray instrument systems, in collaboration with VigeneTech, developers of novel image analysis, automation, and instrumentation software, now offers a platform that combines the superior ... (Thu, 06 Aug 2009 06:05:41 GMT)

Affymetrix And PFGRC At JCVI Unveil FDA-ECSG Custom Microarray
Affymetrix, Inc. (Affymetrix) is engaged in the bu ... Becton, Dickinson and Company (BD) is a medical te ... (Thu, 06 Aug 2009 08:29:12 GMT)

J. Craig Venter Institute offers new Affymetrix array for faster identification of E. coli and shigella
Affymetrix, Inc. and the National Institute of Allergy and Infectious Diseases (NIAID)-supported Pathogen Functional Genomics Resource Center (PFGRC) at the J. Craig Venter Institute (JCVI) today announced the launch of the Affymetrix FDA-ECSG custom microarray for identifying and discriminating between different strains of E. coli and Shigella. (Thu, 06 Aug 2009 09:57:05 GMT)

Novartis' Genomics Institute Partners with JDRF
NEW YORK (GenomeWeb News) – Novartis' genomics research arm will collaborate with the Juvenile Diabetes Research Foundation (JDRF) in a drug discovery and development program focused on Type 1 diabetes, JDRF said on Wednesday. (Thu, 06 Aug 2009 14:45:38 GMT)

New Products
Shimadzu Biotech this week launched its Flexi-Mass-DS polymeric, single-use targets for MALDI analysis. (Thu, 06 Aug 2009 15:00:47 GMT)

Yale researchers find key to keeping cells in shape
( Yale University ) Yale University researchers have discovered how a protein within most cell membranes helps maintain normal cell size, a breakthrough in basic biology that has implications for a variety of diseases such as sickle cell anemia and disorders of the nervous system. (Thu, 06 Aug 2009 16:24:14 GMT)

MDRNA, Inc. to Present at the 29th Canaccord Adams Global Growth Conference
BOTHELL, WA--(Marketwire - August 6, 2009) - MDRNA, Inc. ( NASDAQ : MRNA ) announced today that it will present at the 29th annual Canaccord Adams Global Growth Conference on Wednesday, August 12, 2009, at 3:00 p.m. Eastern Time (12:00 p.m. Pacific Time) at the InterContinental Hotel in Boston, Massachusetts. J. Michael French, MDRNA's President and Chief Executive Officer, will present a ... (Thu, 06 Aug 2009 17:25:28 GMT)

New Clues to How Cells Stay in Shape as Salinity Shifts
Image shows ion cotransporter (blue) in the red blood cell membrane. When it is phosphorlated (white flash) it is inactive, but when it is dephosphorylated it is active, allowing potassium and chloride to leave the cell. (Thu, 06 Aug 2009 17:31:58 GMT)

What makes stem cells tick?
( Burnham Institute ) Investigators at the Burnham Institute for Medical Research and The Scripps Research Institute have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives. (Thu, 06 Aug 2009 18:07:34 GMT)

What makes stem cells tick?
Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives. The data may help stem cell researchers understand the mechanisms that determine whether stem cells divide or differentiate, what types of ... (Thu, 06 Aug 2009 18:15:43 GMT)

Foundations Target Type 1 Diabetes
La Jolla's Genomics Institute of the Novartis Research Foundation said Aug. 5 it has... (Thu, 06 Aug 2009 18:19:56 GMT)

What Makes Stem Cells Tick?
Investigators at the Burnham Institute for Medical Research and The Scripps Research Institute have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives. (Thu, 06 Aug 2009 18:47:21 GMT)

Researchers Find Key To Keeping Cells In Shape
Yale University researchers have discovered how a protein within most cell membranes helps maintain normal cell size, a breakthrough in basic biology that has implications for a variety of diseases such as sickle cell anemia and disorders of the nervous system.Cell size is regulated by the balance of positively and negatively charged ions and other solutes in the fluid inside and outside cells, ... (Thu, 06 Aug 2009 19:09:45 GMT)

NHGRI to Fund Genomics Education, Career Development
NEW YORK (GenomeWeb News) – The National Human Genome Research Institute will fund education programs and training initiatives that are connected to specific NHGRI initiatives or are aimed at spreading new information and approaches. (Thu, 06 Aug 2009 19:30:53 GMT)

Luminex Corporation Reports Second Quarter 2009 Results
AUSTIN, Texas----Luminex Corporation today announced financial results for the second quarter ended June 30, 2009. Recent financial and operating highlights include the following: Consolidated second quarter revenue of $27.8 million, a fourteen percent increase over the second quarter of 2008; and earnings per share of $0.03 System shipments of 158 includes 16 FLEXMAP 3D™ systems, resulting in ... (Thu, 06 Aug 2009 20:01:00 GMT)

SGI chases Cray with baby cluster
Ours is bigger, er, smaller Cray thinks there is a market for baby supercomputers that bridge the gap between fast two-socket workstations with peppy graphics cards and the rack-based parallel supercomputer clusters that run large-scale simulations.… Offloading malware protection to the cloud (Thu, 06 Aug 2009 21:24:02 GMT)

Proteomics helps find key to keeping cells in shape
Yale University researchers have discovered how a protein within most cell membranes helps maintain normal cell size, a breakthrough in basic biology that has implications for a variety of diseases such as sickle cell anemia and disorders of the nervous system. (Fri, 07 Aug 2009 04:11:35 GMT)

Genomics findings offer anti-viral tools
Genomic science, considered by many to be the future of medicine for its ability to identify the unique nature of organisms, took significant steps forward this week through the work of separate research teams at UNC-Chapel Hill and Duke University. (Fri, 07 Aug 2009 06:02:03 GMT)

Scientists shed light on what makes stem cells tick
Washington, August 7 : A team of U.S. scientists has identified phosphorylated signalling proteins in human embryonic stem cells (hESCs) studying which may help understand the mechanisms that determine whether stem cells divide or differentiate, what types of cells they become, and how to control those complex mechanisms to facilitate development of new therapies. (Fri, 07 Aug 2009 07:58:40 GMT)

Innovative Diabetes Drug Discovery And Development Partnership Announced By JDRF And GNF
The Juvenile Diabetes Research Foundation has said that it has entered into a novel collaborative research agreement with the Genomics Institute of the Novartis Research Foundation (GNF) to create a diabetes drug discovery and development platform. (Fri, 07 Aug 2009 10:16:55 GMT)

Penn State Team IDs Expression Changes Linked To Drug Relapse in Rats
NEW YORK (GenomeWeb News) – A team of researchers from Pennsylvania State University has identified dozens of genes whose expression in rat brains changes in concert with drug relapse behavior in heroin-addicted animals. (Fri, 07 Aug 2009 12:45:46 GMT)

The hepatitis healing power of blueberry leaves
( American Society for Biochemistry and Molecular Biology ) A chemical found in blueberry leaves has shown a strong effect in blocking the replication of the hepatitis C virus, opening up a new avenue for treating chronic HCV infections, which affect 200 million people worldwide and can eventually lead to cirrhosis and liver cancer. (Fri, 07 Aug 2009 15:53:17 GMT)

Advances in lung cancer research announced at conference
( The Translational Genomics Research Institute ) Dr. Glen Weiss of the Translational Genomics Research Institute and Scottsdale Healthcare this week announced two significant advances in treating lung cancer at an international cancer research conference. (Fri, 07 Aug 2009 16:22:44 GMT)

UB wants medical schools downtown
The University at Buffalo is negotiating to obtain a huge chunk of property along Goodell Street and Michigan Avenue in the medical corridor for the proposed relocation of its medical schools. (Fri, 07 Aug 2009 16:23:56 GMT)

PLoS Mulls Hosting Software amid Growing Crossover between Informatics and Publishing
As the boundary between databases and journal articles blurs, researchers and publishers are exploring methods to make data and software more readily available with papers, as well as ways to make the growing body of online literature more "database-like" to help users find and share results more easily. (Fri, 07 Aug 2009 16:45:33 GMT)

People in the News
Rafael Irizarry received President's Award by the Committee of Presidents of Statistical Societies in "recognition of outstanding contributions to the statistics profession," according to the announcement. (Fri, 07 Aug 2009 19:15:33 GMT)

In Print
Brown JW, Birmingham A, Griffiths PE, Jossinet F, Kachouri-Lafond R, Knight R, Lang BF, Leontis N, Steger G, Stombaugh J, Westhof E. The RNA structure alignment ontology . [ RNA . 2009 Jul 21. (e-pub ahead of print)]: Multiple sequence alignments are usually shown as two-dimensional matrices, with rows representing individual sequences and columns identifying nucleotides from corresponding ... (Fri, 07 Aug 2009 19:15:43 GMT)

Chemists Rationally Design Inhibitors Against an RNA Molecule that Causes Myotonic Muscular Dystrophy
(PhysOrg.com) -- Chemists at the University at Buffalo have used rational drug design to synthesize small, cell-permeable molecules that are effective in vitro against two common types of myotonic muscular dystrophy, a result that has implications for potentially curing muscular dystrophy, as well as other diseases. (Fri, 07 Aug 2009 19:33:54 GMT)

In Brief This Week
NEW YORK (GenomeWeb News) – Affymetrix said this week that the J. Craig Venter Institute has launched Affy's FDA-ECSG custom microarray for identifying and discriminating between different strains of E. coli and Shigella . The new array is being made freely available to researchers from the National Institute of Allergy and Infectious Diseases-supported Pathogen Functional Genomics Resource ... (Fri, 07 Aug 2009 20:46:13 GMT)

Advances In Lung Cancer Research
Dr. Glen Weiss of the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare this week announced two significant advances in treating lung cancer at an international cancer research conference.Dr. (Fri, 07 Aug 2009 21:22:16 GMT)

Conaway Lab uncovers function of potential cancer-causing gene product
( Stowers Institute for Medical Research ) The Stowers Institute's Conaway Lab has uncovered a previously unknown function of a gene product called Amplified in Liver Cancer 1 (Alc1), which may play a role in the onset of cancer. The work was published yesterday by the Proceedings of the National Academy of Sciences. (Fri, 07 Aug 2009 21:22:34 GMT)

Function Of Potential Cancer-causing Gene Product Uncovered
Scientists have uncovered a previously unknown function of a gene product called Amplified in Liver Cancer 1 (Alc1), which may play a role in the onset of cancer. (Sat, 08 Aug 2009 01:22:52 GMT)

Phosphorylated Signaling Proteins Identified In Human Embryonic Stem Cells
Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives. (Sat, 08 Aug 2009 10:04:24 GMT)

Research: Taxonomy in crisis
Taxonomy is the science of identifying, naming and cataloguing organisms into systems of classification. The challenge is to encourage more students to go into the field, writes FAEZAH ISMAIL. (Sun, 09 Aug 2009 03:17:15 GMT)

What Makes Stem Cells Tick?
Investigators have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives. (Sun, 09 Aug 2009 07:24:35 GMT)

ATTORNEY GENERAL CALLS FOR INCREASED USE OF DNA EVIDENCE
N. C. Attorney General Roy Cooper asked more than 250 scientists and students gathered at a genomics research conference organized by Western Carolina University to join him in his effort to expand the state's DNA database and increase the number of genetic analysts in the State Bureau of Investigation. (Sun, 09 Aug 2009 07:44:20 GMT)

Earhart mystery could be solved with help of DNA lab
Two Ontario DNA labs are hoping to help solve one of the most fascinating mysteries in aviation history: the disappearance of aviation pioneer Amelia Earhart. (Sun, 09 Aug 2009 11:48:06 GMT)

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway
Induced pluripotent stem (iPS) cells can be generated from somatic cells by the introduction of Oct3/4 (also known as Pou5f1), Sox2, Klf4 and c-Myc, in mouse and in human. The efficiency of this process, however, is low. Pluripotency can be induced without c-Myc, but with even lower efficiency. A p53 (also known as TP53 in humans and Trp53 in mice) short-interfering RNA (siRNA) was recently ... (Sun, 09 Aug 2009 17:06:59 GMT)

Market accessibility major issue for local ICT firms
CYBERJAYA: One of the biggest challenges to developing a Malaysian information and communications technology (ICT) global giant is market accessibility, according to Multimedia Development Corp Sdn Bhd (MDeC) vice-president of industry development division Saifol Shamlan. (Sun, 09 Aug 2009 23:38:59 GMT)

Chemists rationally design inhibitors against an RNA molecule that causes myotonic muscular dystrophy
Chemists at the University at Buffalo have used rational drug design to synthesize small, cell-permeable molecules that are effective in vitro against two common types of myotonic muscular dystrophy, a result that has implications for potentially curing muscular dystrophy, as well as other diseases. (Mon, 10 Aug 2009 00:44:20 GMT)

Protein Structures Revealed At Record Pace
The structure of a protein in days -- not months or years -- ushers in a new era in genomics research. Scientists have developed a high-throughput protein pipeline that could expedite the development of biofuels, and elucidate how proteins carry out life's vital functions. (Mon, 10 Aug 2009 08:23:15 GMT)

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