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Age-defying dinosaur collagen
Hadrosaur, dead 80 million years, yields oldest protein yet sequenced. (Fri, 01 May 2009 00:35:08 GMT)
National Institute of Statistical Sciences Hires Six New Postdoctoral Fellows
Triangle - The National Institute of Statistical Sciences (NISS), a research institute created by the national statistical sciences community, has appointed six new postdoctoral fellows. The fellows will participate in several new research programs at NISS. (Fri, 01 May 2009 02:05:02 GMT)
New cattle breeding era to flow from gene blueprint
The sequencing of the bovine genome announced last week is set to deliver a new finesse to the business of cattle breeding, and to beef and dairy production. (Fri, 01 May 2009 03:23:00 GMT)
New cattle breeding era to flow from gene blueprint
The sequencing of the bovine genome announced last week is set to deliver a new finesse to the business of cattle breeding, and to beef and dairy production. (Fri, 01 May 2009 03:23:02 GMT)
Climate change threatens Lake Baikal's unique biota
( American Institute of Biological Sciences ) The diverse biota of Lake Baikal, the world's largest lake, will come under severe pressure as the climate becomes warmer and wetter, because the food web relies on a long period of ice cover to shelter microbes that generate the annual production of organic carbon. The lake's top predator is also vulnerable to a reduction in ice cover. Pollution and ... (Fri, 01 May 2009 04:04:46 GMT)
Study: Plant 'stress hormone' key to combating drought
A team of scientists from Canada, Spain and the United States has identified a key gene that allows plants to defend themselves against environmental stresses like drought, freezing and heat. (Fri, 01 May 2009 05:41:23 GMT)
Dendreon Drug Prolongs Life, ZymoGenetics Cuts Staff, Microsoft Tackles Biotech & More Seattle-Area Life Sciences News
This week, Seattle biotech got some of the best news it has seen in years. One local biotech company, Dendreon, scored a major coup by generating results that show its immune-boosting drug for prostate cancer can prolong life with minimal side effects. But there was a lot more happening in the local lab scene than ... (Fri, 01 May 2009 06:34:11 GMT)
CombiMatrix Corporation to Release First Quarter Financial Results On May 6, 2009
MUKILTEO, Wash., May 1, 2009 -- CombiMatrix Corporation announced today that it will release its first quarter 2009 financial results on Wednesday, May 6, 2009. Results will be released at the close of trading on that day. (Fri, 01 May 2009 10:00:00 GMT)
Arrayit To Mass Produce Rapid H1N1 Swine Flu Test Chip
Arrayit Corporation (OTC Bulletin Board: ARYC), a leading manufacturer of products and services for disease prevention, treatment and cure, announced that it is developing a microarray-based diagnostic test to detect the H1N1 swine flu virus. (Fri, 01 May 2009 12:18:53 GMT)
Context Network founding partner Tray Thomas is featured speaker at international genomics conference
“Creating value is not equivalent to capturing value.” That’s according to Context Network founding partner, Tray Thomas who was a featured speaker at the fourth annual international Genomics in Business conference in Amsterdam, The Netherlands. (Fri, 01 May 2009 14:49:04 GMT)
Luminex Corporation to Present at Bank of America and Merrill Lynch 2009 Health Care Conference
AUSTIN, Texas----Luminex Corporation today announced that management will present at the Bank of America and Merrill Lynch 2009 Health Care Conference to be held May 12-14, 2009, in New York. (Fri, 01 May 2009 15:00:00 GMT)
Lab models swine flu's spread; diagnostic chips being readied
A Virginia Tech lab has been modeling the spread of swine flu as chip makers work to develop diagnostic tools to stop the H1N1 flu virus. (Fri, 01 May 2009 15:02:10 GMT)
Blog - The Leonardo paradox
Science has long used the singular genius model. Is this interfering with translating bio-research into something useful? (Fri, 01 May 2009 15:34:23 GMT)
Sequenom Faces Class Action Lawsuits
NEW YORK (GenomeWeb News) – Sequenom is facing class-action lawsuits brought on behalf of shareholders following the firm's announcement Wednesday that it would delay the launch of its SEQureDx Down syndrome test until the third quarter of this year after it discovered that company employees had mishandled R&D test data and results. (Fri, 01 May 2009 15:48:09 GMT)
Overbrook to Distribute Phytronix Ionization Technology
NEW YORK (GenomeWeb News) – Overbrook Scientific will distribute Phytronix's laser diode thermal desorption ionization technology to labs in the US, under an agreement announced today. (Fri, 01 May 2009 15:48:15 GMT)
This Week in Science
The big news published in the early online edition of Science this week is the largest study ever of African genetic diversity , led by the University of Pennsylvania's Sarah Tishkoff. (Fri, 01 May 2009 16:02:53 GMT)
Oops, Fake-Out
Merck published a journal containing reprinted or review articles that reported data favorable to the drug company, all without disclosing its sponsorship of the journal, says The Scientist . The journal, called the Australasian Journal of Bone and Joint Medicine , was published by a division of Elsevier, to which Merck paid an undisclosed sum, the article says. (Fri, 01 May 2009 16:03:03 GMT)
Engaging Slim Shady
Janet Stemwedel first asked her readers what they would do if they were working with a scientist they feel might be "shady." Many of her readers says that they'd run from the situation, though they acknowledge they should try to get more information. (Fri, 01 May 2009 16:03:23 GMT)
Get it Straight: Simple Steps to Improve Your Posture
As National Correct Posture Month, May is the perfect time to focus on keeping your spine healthy. University of the Sciences in Philadelphia's Assistant Professor of Physical Therapy Dr. Greg Thielman offers simple exercises and solutions to improve your posture--and avoid a lifetime of aches and pains. (Fri, 01 May 2009 17:29:12 GMT)
Novel carrier proteins derived from Staphylococcus nuclease for high yield peptide production, L-11391
Novel carrier proteins for the production of small or large peptides as recombinant fusion proteins. (Fri, 01 May 2009 18:06:39 GMT)
ISRO to send bacteria cells into space
Bangalore: In its first set of biological experiments, the Indian Space Research Organisation (ISRO) will send bacteria cells into space — and bring them back — in the second Space Capsule Recovery Experiment (SRE-2) scheduled for ... (Fri, 01 May 2009 19:28:45 GMT)
NHGRI Starts Phase II of Long-Range Planning
NEW YORK (GenomeWeb News) – The National Human Genome Research Institute has started the second phase of its long-term planning process, and has called on the research community and interested parties to comment on recent updates it has made to a series of white papers it released at the end of last year. (Fri, 01 May 2009 20:02:53 GMT)
People in the News
Gene Network Sciences announced it named Robert Ruffolo , former President of Wyeth Research & Development to its scientific advisory board. (Fri, 01 May 2009 20:47:55 GMT)
Bioinformatics Briefs
Software and consulting firm InforSense announced that Celera is using the firm's platform to integrate internal molecular and public data as part of their project to identify biomarkers. (Fri, 01 May 2009 21:02:54 GMT)
Downloads and Upgrades
In a joint statement, the companies point out that this venture is a reaction to the needs of researchers using second-generation sequencing platforms with "vast amounts of sequencing data" that requires "many hours and computing resources to manage, distribute, and analyze the data." (Fri, 01 May 2009 21:03:04 GMT)
CSC Consultants Try to Help Life-Sci Move Toward Integration and Greater Agility
Business technology-consulting firm Computer Sciences Corporation has published a white paper on "the next generation of R&D" that suggests some IT-based approaches that could help pharma replenish pipelines. (Fri, 01 May 2009 21:18:05 GMT)
Around the Regions
The governing board of the California Institute for Regenerative Medicine, the state's stem cell agency, this week awarded 15 Early Translational research grants totaling $67.7 million, with the goals of aiding development of drug candidates for unmet medical needs, and addressing bottlenecks in the development of new therapies. (Fri, 01 May 2009 21:18:15 GMT)
Microsoft Takes Aim at Life-Sci Community with New Platform and New Partnerships
Boston --Microsoft this week introduced its Amalga Life Sciences software to help integrate healthcare and life science research data. (Fri, 01 May 2009 21:32:52 GMT)
BioRegion Real Estate
The Massachusetts Biotechnology Council, the Bay State's life sciences industry group, on April 30 announced its first set of communities rated the readiest to accommodate life-sciences companies seeking to relocate to or expand within the Bay State. (Fri, 01 May 2009 21:33:03 GMT)
Life-Sci REITs HCP and BioMed Realty Report Q1 Financials; Update Leasing, Financing Activity
HCP and BioMed Realty , two of the nation's largest publicly-traded owners of life sciences space, offered largely upbeat updates on their leasing, financing, and first-quarter results during separate conference calls earlier this week following release of their quarterly financial results. (Fri, 01 May 2009 22:02:53 GMT)
ISRO to send bacteria cells into space
Biological experiments will be a prelude to manned mission (Fri, 01 May 2009 22:12:21 GMT)
Date Palm Genome Drafted
Researchers have mapped a draft version of the date palm genome, unlocking many of its genetic secrets. (Sat, 02 May 2009 03:33:53 GMT)
Flu chip fights pig plague
Pick your pandemic As swine-flu mania continues to suck up every available nanosecond of fear-mongering media maundering, one small company has developed a sure-fire way to detect the potent piggy pathogen.… Whitepaper - Real time protection for Hyper-V (Sat, 02 May 2009 06:12:26 GMT)
Genomics And Darwinism: Genome Research Publishes Special Issue
The May 2009 issue of Genome Research is a special issue celebrating the 200th anniversary of Charles Darwin's birth, and the 150th anniversary of the publication of On the Origin of Species. Published online, the issue features a collection of perspective reviews and primary research in comparative genomics, genome evolution, and population genomics. (Sat, 02 May 2009 10:18:33 GMT)
Means To Measure Possible Leukemia Marker Validated By Study
A study led by cancer researchers at The Ohio State University has validated a method for reliably measuring variations in certain proteins that may make good biomarkers in chronic leukemia patients. The study shows that liquid chromatography-mass spectrometry (LC-MS) can measure variations in histones, which are spool-like proteins that help support and store DNA. (Sat, 02 May 2009 10:19:04 GMT)
Moving Target: CNVs in Disease
Over the past year, a slew of papers emerged linking copy number variation to a host of diseases. It's no wonder that studies linking insertions and deletions to disease etiology continue to multiply. (Sat, 02 May 2009 11:47:53 GMT)
There is much still left to understand about H1N1
While fears about the H1N1 virus are abating somewhat, virologists say we shouldn't let our guard down yet. Influenza viruses are notorious for their ability to mutate. (Sat, 02 May 2009 11:50:26 GMT)
Get It Straight: Simple Steps To Improve Your Posture
As National Correct Posture Month, May is the perfect time to focus on keeping your spine healthy. University of the Sciences in Philadelphia's Assistant Professor of Physical Therapy Dr. Greg Thielman offers simple exercises and solutions to improve your posture and avoid a lifetime of aches and pains. (Sat, 02 May 2009 13:03:23 GMT)
Bio-IT World expands newsletter offerings
According to the newsletter's editor, Malorye Branca, the newsletter aims to keep readers abreast of the major developments in pharmacogenomics and identifies the issues that will have the greatest impact on their businesses. (Sat, 02 May 2009 18:23:59 GMT)
Adapting Assays for Clinical Applications
By Larry Hand April 1, 2008 | Sometimes, it helps to think smaller or, in this case, less dense. The capability of DNA microarrays to produce copious amounts of data can make it difficult to extract clinically applicable meaning from (Sat, 02 May 2009 18:28:20 GMT)
23andMe’s Price Cut: The End of Commercial Personal Genomics?
BNet | ANALYSIS | A huge price cut by personal-genomics pioneer 23andMe may well herald the demise of the commercial personal-genomics business before it even really got started — and for much the same reason that startups such as Celera Genomics saw their genome-based information businesses crash and burn almost a decade ago. (Sat, 02 May 2009 18:29:39 GMT)
23andMe: Avey Proposes New Personal Genomics Paradigm
Bio-IT World | 23andMe cofounder Linda Avey wowed the audience at the 2008 Bio-IT World Expo with her keynote presentation on the possibilities for personal genomics. (Sat, 02 May 2009 18:29:47 GMT)
‘Once More Unto the Breach…’
By Malorye A. Branca September 15, 2003 | With public celebrations in 2000, 2001, and earlier this year, one could be forgiven for believing that the human genome has been sequenced in its entirety. But much uncharted territory remains in the genome. Although the International Human Genome Sequencing Consorti (Sat, 02 May 2009 18:32:39 GMT)
Bio-IT World expands newsletter offerings
According to the newsletter's editor, Malorye Branca, the newsletter aims to keep readers abreast of the major developments in pharmacogenomics and identifies the issues that will have the greatest impact on their businesses. (Sat, 02 May 2009 19:09:02 GMT)
‘E-source’ Is Coming, Experts Say
Odd marriages of the ancient and modern are the rule in clinical technologies and were much in evidence at the E-Clinical Trials & Research conference program of the 2005 Bio-IT World Conference + Expo . There was heartening evidence of the adoption of advanced and robust commercial software — even toward clinical trials that do not use paper. (Sat, 02 May 2009 19:11:07 GMT)
Around the Bases Oct. 2, 2003
First Base: Systems Are Go Elias Zerhouni, the director of the National Institutes of Health (NIH), has given his backing to the fledgling field of systems biology. (Sat, 02 May 2009 19:15:38 GMT)
‘Information-Based Medicine’ (or IBM for Short)
By Nancy Weil, IDG News Service April 15, 2003 | The convergence of life sciences and IT, now in its early stages, means that we’ll live longer because doctors have better access to data that will help them prevent, diagnose, and treat diseases, said Caroline Kovac, general manager of IBM’s life sciences gro (Sat, 02 May 2009 19:16:53 GMT)
In Dog Study, Scientists Rescue Dystrophin Function with Morpholinos
Using morpholinos to induce exon skipping, researchers rescued some dystrophin function in dogs with the canine form of Duchenne muscular dystrophy. (Sat, 02 May 2009 19:17:53 GMT)
Common Genetic Factors That Affect Autism Risk Have Been Identified
The first common genetic risk factor for autism spectrum disorder has been identified by a multi-center team of researchers that included Margaret Pericak-Vance, Ph.D., director of the Miami Institute for Human Genomics at the University of Miami Miller School of Medicine. Dr. Pericak-Vance and her collaborator Jonathan Haines, Ph.D. (Sat, 02 May 2009 20:02:15 GMT)
A Mayor, A Maverick, and Microbes Galore
While the rest of the time zone was settling down to primetime television last night, the genetics community gathered here in Philadelphia was settling in for its own evening of entertainment. (Sat, 02 May 2009 21:18:34 GMT)
MAQC, LabCorp, Veridex, Qiagen, Epigenomics, NIH, Philips Life Sciences, Organon, 23andMe, Population Genomics ...
CARY, NC — The MicroArray Quality Control Consortium has expanded its scope by adding a new workgroup that will identify “best practices” for genome-wide association studies. (Sat, 02 May 2009 22:17:55 GMT)
My Pharmiweb.com
AnaSpec Inc. San Jose, CA – May 1, 2009 AnaSpec has announced the release of the newest addition to its Anti-MOG ELISA assay kit series – the SensoLyteÒ Anti-Human MOG (1-125) IgG Quantitation ELISA Kit. This kit, along with previously featured SensoLyteÒ Anti-Mouse MOG (1-125) and SensoLyteÒ Anti-Rat MOG (1-125) IgG ELISA assay kits are useful for determining the amount of anti-human MOG ... (Sun, 03 May 2009 08:49:12 GMT)
Analyze This Proteome
Analyzing proteins is about trade-offs. Do you want to take a top-down approach or a bottom-up? Will you get the information you need from looking at the proteins or by looking at the peptides? (Sun, 03 May 2009 09:17:53 GMT)
Medical Center Briefs: Few trainers follow protocol for asthma, OSU study shows
OSU seeks to improve NCAA asthma care Very few athletic trainers associated with National Collegiate Athletic Association (NCAA) programs said that they were following best practice standards for managing asthma among their athletes, according to a new study. (Mon, 04 May 2009 01:53:32 GMT)
Collecting Sets of Genes
Many large-scale biology projects make use of a complete set of genes for one's favorite species. Working on such projects for a number of years, we're often reminded that the seemingly straightforward task of assembling a complete list of genes is not so easy, even for our favorite species — human. (Mon, 04 May 2009 03:02:54 GMT)
Panasas And Dell Introduce Integrated, High-Performance Solution For Life Sciences Research
Panasas, Inc., the leading provider of storage for the world's most performance-intensive applications, recently announced that the company has partnered with Dell to deliver an integrated, high-performance, clustered computing solution for the life sciences research community. (Mon, 04 May 2009 05:45:40 GMT)
Five UCSF Scientists Elected to National Academy of Sciences
Five UCSF faculty scientists are among the 72 new members and 18 foreign associates from 15 countries elected recently to the National Academy of Sciences, the Academy has announced. (Mon, 04 May 2009 07:01:00 GMT)
Five UCSF Scientists Elected to National Academy of Sciences
Five UCSF faculty scientists are among the 72 new members and 18 foreign associates from 15 countries elected recently to the National Academy of Sciences, the Academy has announced. (PRWeb May 4, 2009) Read the full story at http://www.prweb.com/releases/UC (Mon, 04 May 2009 07:13:57 GMT)
Lab models swine flu's spread; diagnostic chips being readied
PORTLAND, Ore. — Swine flu may have been caught early enough to prevent a serious U.S. epidemic, according to computer models developed by Virginia Tech's Network Dynamics and Simulation Science Laboratory (NDSSL). (Mon, 04 May 2009 11:02:42 GMT)
Unlocking The Genetic Secrets Of The Date Palm Has Implications For Biomedical Research
Researchers at Weill Cornell Medical College in Qatar (WCMC-Q) have mapped a draft version of the date palm genome, unlocking many of its genetic secrets. "We have generated a draft DNA sequence and initial assembly of the date palm using the most advanced technology," says Joel Malek, director of the Genomics Laboratory at Weill Cornell Medical College in Qatar. (Mon, 04 May 2009 11:03:43 GMT)
Invitrogen Develops New Technology to Promote Safer Stem Cell Therapies
CARLSBAD, Calif.----Invitrogen, a division of Life Technologies , today announced a new technology to enable the development of safer stem cell therapies. Dynabeads® SSEA-4, addresses a key challenge in translational research by separating undifferentiated stem cells from those that are differentiated. (Mon, 04 May 2009 11:30:00 GMT)
Ocimum Biosolutions to Introduce New Test for the H1N1 Flu
HYDERABAD, India----Ocimum Biosolutions announced the launch of a microarray-based test for the latest version of the H1N1 flu. The company reported that it updated its custom chip probes using sequence information from the latest strain of the swine flu from the NCBI site. (Mon, 04 May 2009 13:00:00 GMT)
Health Discovery Corporation Names R. Scott Tobin as President and General Counsel
SAVANNAH, Ga.----Health Discovery Corporation , a molecular diagnostics company specializing in personalized medicine, today announced the appointment of R. Scott Tobin as President and General Counsel, effective April 15. (Mon, 04 May 2009 13:20:00 GMT)
Swine flu research may spread to Van Andel Institute in Grand Rapids
As schools in West Michigan take precautions, the Translational Genomics Research Institute, an Arizona lab with a local alliance, is on the case. (Mon, 04 May 2009 13:24:51 GMT)
With $60M, HHMI Funds HIV-TB Research Institute in South Africa
The Howard Hughes Medical Institute partnered with the University of KwaZulu-Natal in Durban, South Africa, to build an international research center focused on fighting co-infection of tuberculosis and HIV, two diseases that are ravaging that area of the world. (Mon, 04 May 2009 13:32:54 GMT)
Genetic Secrets Of Date Palm Unlocked By Researchers At Weill Cornell Medical College In Qatar
Researchers at Weill Cornell Medical College in Qatar (WCMC-Q) have mapped a draft version of the date palm genome, unlocking many of its genetic secrets. "We have generated a draft DNA sequence and initial assembly of the date palm using the most advanced technology," says Joel Malek, director of the Genomics Laboratory at Weill Cornell Medical College in Qatar. (Mon, 04 May 2009 14:19:11 GMT)
Ontario to award $100M for genomics research
The Ontario government has announced $100 million in new funding for genomics research, an effort to attract top researchers from around the world and keep them in the province. (Mon, 04 May 2009 14:28:10 GMT)
Clinical Data in Cancer PGx Alliance with Univ. of Pittsburgh
NEW YORK (GenomeWeb News) – Clinical Data today said that it has started a collaboration with the University of Pittsburgh to discover and validate genetic variants that could predict response to certain cancer treatments. (Mon, 04 May 2009 14:48:14 GMT)
BD, Fujirebio Partner on Cancer Dx Assays
NEW YORK (GenomeWeb News) – Becton Dickinson and Fujirebio Diagnostics have inked a worldwide development and supply agreement for multiplex oncology diagnostic assays. (Mon, 04 May 2009 14:48:26 GMT)
NIDDK, NHLBI Seek Non-invasive Disease Tests
NEW YORK (GenomeWeb News) – The National Institutes of Health will fund development of new non-invasive methods for diagnosis and monitoring of the progression of diabetes, kidney, urological, hematological, and digestive diseases and kidney disorders, with grants covering up to five years of research. (Mon, 04 May 2009 14:48:37 GMT)
Protein analysis methods, viral vectors featured in Cold Spring Harbor Protocols
( Cold Spring Harbor Laboratory ) The May issue of "Cold Spring Harbor Protocols" features a set of methods that can be used to analyze protein complexes. An additional featured article details the generation of viral vectors for gene transfer. (Mon, 04 May 2009 14:53:31 GMT)
Big Data: SSD's, R, and Linked Data Streams
If you haven't seen it, I recommend you watch Andy Bechtolsheim's keynote at the recent Mysqlconf. We covered SSD's in our just published report on Big Data management technologies. Since then, we've gotten additional signals from our network of alpha geeks and our interest in them remains high. I had a chance to visit with Dataspora founder and blogger Mike Driscoll, an enthusiastic advocate ... (Mon, 04 May 2009 15:27:46 GMT)
This Week in PLoS
In PLoS Computational Biology this week, scientists from the Hungarian Academy of Sciences in Budapest describe a method to predict the disordered binding regions of intrinsically unstructured/disordered proteins. (Mon, 04 May 2009 16:02:53 GMT)
Santaris Q1 Loss Narrows, Completes Phase I Trial of miRNA HCV Rx
Santaris Pharma last week issued its interim financial report for the first quarter of 2009, posting a more than 60 percent improvement in its quarterly loss on a surge in revenues. (Mon, 04 May 2009 16:17:53 GMT)
The Online Information Source for the Medical Device Industry
More point-of-care testing, more multiplexing, and more-automated sample preparation are the big innovations for in vitro diagnostics manufacturers working in detection. (Mon, 04 May 2009 17:07:53 GMT)
Sequenom Shares Hammered, Affy's Shares Continue Rebound in April
NEW YORK (GenomeWeb News) – Stocks in the GenomeWeb Daily News Index continued their rebound for the second straight month, with Affymetrix rising sharply for the second time in as many months. (Mon, 04 May 2009 18:03:14 GMT)
Shilatifard and colleagues clarify the enzymatic activity of factors involved in childhood leukemia
The Stowers Institute's Shilatifard Lab and colleagues have provided new insight into the molecular basis for H3K4 methylation, an activity associated with the MLL protein found in chromosomal translocation-based aggressive infant acute leukemias. Studies describing these collaborative studies were published online by Molecular and Cellular Biology and Cell this week. (Mon, 04 May 2009 18:13:39 GMT)
Ontario to award $100M for genomics research
The Ontario government has announced $100 million in new funding for genomics research, an effort to attract top researchers from around the world and keep them in the province. (Mon, 04 May 2009 18:33:52 GMT)
Cooke to retire from Canisius
The president of Canisius College is stepping down next year, according to a release issued Monday by the college. (Mon, 04 May 2009 18:38:08 GMT)
Q&A: Large-scale Study Explores Protein Changes that Persist in Cocaine Use, Even After Long Periods of Abstinence
In a study published March 17 in the online edition of Proteomics-Clinical Applications, a team of researchers looked at the protein changes in rats that had been exposed to cocaine. (Mon, 04 May 2009 19:17:53 GMT)
ABI Cites Applied Markets, New Instruments for 'Good' MS Quarter; Analyst Says Bruker 'Key Beneficiary' of Stimulus ...
Life Technologies said last week that its mass spectrometry business, housed in its Applied Biosystems group, performed above expectations in the first quarter of 2009 due to shipments of new instruments during the quarter and growth in the applied markets. (Mon, 04 May 2009 19:18:03 GMT)
NCI, Canary Seek Non-smoking Lung Cancer Causes
NEW YORK (GenomeWeb News) – The National Cancer Institute and the Canary Foundation are partnering to fund a number of studies aimed at understanding the genetic causes of lung cancer in non-smokers and developing early-stage diagnostics. (Mon, 04 May 2009 19:47:55 GMT)
ARUP Licenses Ipsogen Leukemia MDx IP
NEW YORK (GenomeWeb News) – French molecular diagnostics company Ipsogen has licensed rights to use gene variants for diagnosing leukemia to ARUP Laboratories, a reference lab that is part of the University' of Utah's Department of Pathology. (Mon, 04 May 2009 19:48:04 GMT)
QIAGEN Reports First Quarter 2009 Results
VENLO, The Netherlands, May 4, 2009 -- QIAGEN N.V. today announced the results of operations for its first quarter ended March 31, 2009. (Mon, 04 May 2009 20:00:00 GMT)
DJ HUGIN NEWS/QIAGEN Reports First Quarter 2009 -3-
Corporate news announcement processed and transmitted by Hugin AS. (Mon, 04 May 2009 20:54:18 GMT)
Qiagen Posts 7 Percent Q1 Sales Gain; Profit Rises
NEW YORK (GenomeWeb News) – Qiagen reported after the close of the market on Monday that its first-quarter revenues rose 7 percent while its net income jumped around 22 percent year over year. (Mon, 04 May 2009 21:02:56 GMT)
04.05.2009 - DJ HUGIN NEWS/QIAGEN Reports First Quarter 2009 Results
Corporate news announcement processed and transmitted by Hugin AS. The issuer is solely responsible for the content of this announcement. =--------------------------------------------------------------------- =------------- (Mon, 04 May 2009 21:15:31 GMT)
University of Colorado Licenses Flu Dx Tech to InDevR; Test May Help ID Swine Strain Faster
InDevR, a biotech firm founded in 2003 by researchers at the University of Colorado, Boulder, has licensed from the university an array-based diagnostic chip for identifying various strains of the flu virus, including the swine H1N1 virus, the company said last week. (Mon, 04 May 2009 21:17:53 GMT)
New paradigm identifies gene responsible for acetaminophen-induced liver injury
Acetaminophen (Tylenol and generics) is one of the most commonly used over-the-counter drugs in the United States. While generally safe, acetaminophen is known to cause severe liver injury if taken in high doses. In a study published online in Genome Research, scientists have found a genetic marker linked to the risk of acetaminophen-induced liver injury, using a strategy that will help develop ... (Mon, 04 May 2009 21:23:41 GMT)
MDx Sales Drive 42 Percent Increase in Q3 Revenues for Myriad Genetics
NEW YORK (GenomeWeb News) – Myriad Genetics reported after the close of the market on Monday that its third-quarter revenues increased 42 percent, driven by a sharp uptick in molecular diagnostics sales. (Mon, 04 May 2009 21:47:53 GMT)
Obama riles high-tech exec over outsourcing
Carl Guardino usually comes across as an amenable, mild-mannered Silicon Valley executive. But not on Monday. Not when he watched President Obama promising to end overseas tax breaks for U.S. companies that "create a job in Bangalore, India, (rather than) one... (Tue, 05 May 2009 04:33:33 GMT)
Ocimum Biosolutions to introduce new test for H1N1 flu
Hyderabad, May 4 (Business Wire India): Ocimum Biosolutions announced the launch of a microarray-based test (research use only) for the latest version of the H1N1 flu. (Tue, 05 May 2009 04:46:12 GMT)
Obama riles high-tech exec over outsourcing
Carl Guardino usually comes across as an amenable, mild-mannered Silicon Valley executive. But not on Monday. Not when he watched President Obama promising to end overseas tax breaks for U.S. companies that "create a job in Bangalore, India, (rather than) one... (Tue, 05 May 2009 07:38:03 GMT)
Gene grant just shuffling money: Critics
Ontario's top gene scientists got a $100-million boost to conduct research yesterday -- just days after aspiring undergrads took a grant cut worth the same amount. (Tue, 05 May 2009 09:34:48 GMT)
"Food mill" for proteins - new method improves protein analysis considerably
Until now, extracting as many proteins as possible from biological samples has required a combination of several methods. (Tue, 05 May 2009 11:20:22 GMT)
Ocimum to launch new test for swine flu
Hyderabad, May 5 : Ocimum Biosolutions announced the launch of a microarray-based test (research use only) for the latest version of H1N1 flu (swine flu). (Tue, 05 May 2009 11:22:47 GMT)
Stellar Pharmaceuticals Inc. Signs Licensing Agreement for Distribution and Sale of Uracyst(R) in Italy
Expansion of Stellar's Global Strategy (Tue, 05 May 2009 11:42:06 GMT)
Donors give Case Western medical school $8.7M
CLEVELAND -- At a time when many colleges are struggling to pull in donations, Case Western Reserve University in Cleveland has announced $8.7 million in new gifts for its medical school. (Tue, 05 May 2009 11:59:36 GMT)
What Can You Do with XMPP?
XMPP: The Definitive Guide covers everything you need to know about Extensible Messaging and Presence Protocol (XMPP). This open technology for real-time collaboration, social networking, microblogging, lightweight middleware, cloud computing, and more. This excerpt provides a high-level overview of the technology and introduces you to the ways it's being used. Read more about XMPP. (Tue, 05 May 2009 12:42:46 GMT)
Ocimum Biosolutions B.V. Introduces Affymetrix Services in Europe
IJSSELSTEIN, Netherlands----In line with its strategic objective to build a global network of service centers in close proximity to leading genomics researchers, Ocimum Biosolutions B.V. today announced the launch of genomic services on Affymetrix platform from Europe. (Tue, 05 May 2009 13:00:00 GMT)
University at Buffalo, SUNY, Leads Data-Intensive Discovery Initiative Via an Academic, Government and Industry ...
MARLBOROUGH, Mass.----Netezza Corporation , the global leader in data warehouse and analytic appliances, today announced that the academic, government and industry consortium the Data Intensive Computing Initiative has emerged and has entered its second phase by deploying Netezza's largest appliance in open science. (Tue, 05 May 2009 13:00:00 GMT)
Breast health center gives TGen new research opportunities
( The Translational Genomics Research Institute ) Today's opening of a new breast health center next to John C. Lincoln Deer Valley Hospital will provide significant research opportunities for the Translational Genomics Research Institute. The 9,000-square-foot Breast Health and Research Center will include a tumor biorepository for TGen that will aid the non-profit research institute in ... (Tue, 05 May 2009 13:13:17 GMT)
Medical research gets personal
IAN Frazer is a man excited by the rise of personalised medicine, where genes are used to "fingerprint" which cancers are risky for individuals, and help tailor therapies for them. (Tue, 05 May 2009 14:00:00 GMT)
Illumina Files Patent Infringement Suit Against Affymetrix
SAN DIEGO----Illumina, Inc. today announced that it has filed a patent infringement suit against Affymetrix, Inc. . The suit, filed in United States District Court for the Western District of Wisconsin, asserts that Affymetrix' GeneChip® HT Array Plate and GeneChip® HT Array Plate Scanner infringe upon Illumina's United States Patent No. 7,510,841. (Tue, 05 May 2009 14:40:00 GMT)
Stowers researchers develop whole genome sequencing approach for mutation discovery
( Stowers Institute for Medical Research ) The Stowers Institute's Hawley Lab and Molecular Biology Facility have developed a "whole-genome sequencing approach" to mapping mutations in fruit flies. The novel methodology promises to reduce the time and effort required to identify mutations of biological interest. The work was published in the May issue of the journal Genetics. (Tue, 05 May 2009 16:08:58 GMT)
Integrated Genomics, Inc. Appoints Jose Laplaza, Ph.D. as Director of Strain Engineering and Lab Operations
CHICAGO----Integrated Genomics, Inc. today announces it has appointed Jose Laplaza, Ph.D. as Director of Strain Engineering and Lab Operations. Dr. Laplaza brings significant experience in gene expression, fermentation optimization and strain development. (Tue, 05 May 2009 16:42:00 GMT)
Illumina files patent infringement suit against Affymetrix
Illumina, Inc. (NASDAQ:ILMN) today announced that it has filed a patent infringement suit against Affymetrix, Inc. (“Affymetrix”). (Tue, 05 May 2009 17:03:34 GMT)
InDevR's FluChip detects and distinguishes swine-origin H1N1 from human influenza viruses
( University of Colorado at Boulder ) InDevR of Boulder, Colo. and the Influenza Division of the Centers for Disease Control and Prevention in Atlanta confirmed today that a version version of InDevR's FluChip can detect and distinguish swine-origin H1N1 influenza A viruses from seasonal influenza viruses (A/H1N1 and A/H3N2) as well as the deadly avian A/H5N1 virus. (Tue, 05 May 2009 17:09:23 GMT)
New Product Watch
SAS last week introduced JMP Genomics 4.0 , a software tool for analyzing and exploring data from a variety of high-throughput studies, including microarray experiments. (Tue, 05 May 2009 17:17:58 GMT)
Clarifying The Enzymatic Activity Of Factors Involved In Childhood Leukemia
The Stowers Institute's Shilatifard Lab and colleagues have provided new insight into the molecular basis for H3K4 methylation, an activity associated with the MLL protein found in chromosomal translocation-based aggressive infant acute leukemias. Studies describing these collaborative studies were published online by Molecular and Cellular Biology and Cell this week. (Tue, 05 May 2009 17:18:03 GMT)
Paired Ends
Gina Raimondo will be joining the board of directors of nanopore sequencing startup Nabsys . She is a general partner of Point Judith Capital , the lead investor in Nabsys' recent $4 million equity round. (Tue, 05 May 2009 17:18:18 GMT)
BioInformatics, LLC New Report - Capitalizing on New Opportunities for Stem Cell Products, Now Available
BioInformatics, LLC announces the release of its newest report, Capitalizing on New Opportunities for Stem Cell Products. Despite a sluggish economy and cuts being made to laboratory budgets, the market for stem cell research products is expected to increase substantially over the next several years to $688.9 M in 2009 and just under one billion at the end of 2011. (Tue, 05 May 2009 17:29:00 GMT)
IP Roundup
The National Institute of Advanced Industrial Science and Technology of Tsukuba, Japan, and Dainippon Screen of Kyoto, Japan, have received US Patent No. 7,527,692, "Processing apparatus which performs predetermined processing while supplying a processing liquid to a substrate." (Tue, 05 May 2009 17:33:08 GMT)
Papers of Note
The genome sequence of the psychrophilic archaeon, Methanococcoides burtonii: the role of genome evolution in cold adaptation. Allen MA, Lauro FM, Williams TJ, Burg D, Siddiqui KS, et al. (Tue, 05 May 2009 17:33:32 GMT)
New Products
SAS has released JMP Genomics 4.0 for genomic data analysis. The new version combines capabilities of SAS 9.2 and JMP 8 . It provides new statistical tools for quality control, normalization, and pattern discovery for the analysis of multiple data types from different platforms. (Tue, 05 May 2009 17:33:43 GMT)
Personal Genome Project to Enroll 100 More Participants This Summer; Seeks to Raise $1.5M in Donations
The Personal Genome Project plans to increase its enrollment by 100 this summer, following approval by Harvard Medical School's Institutional Review Board of revised consent forms and procedures for the project, according to a newsletter posted on the project's website last month. (Tue, 05 May 2009 18:02:59 GMT)
With Upcoming iScan Module, Illumina Looks to 'Transition' Array Users to Sequencing
Illumina is developing a new sequencing module for its iScan array scanner that it expects to launch later this year, according to company officials. (Tue, 05 May 2009 18:03:06 GMT)
Ontario Pledges $85M for Genomics
NEW YORK (GenomeWeb News) – Ontario plans to start a large funding program focused on genomics research that aims to lure talented researchers to the area. (Tue, 05 May 2009 19:02:54 GMT)
La Jolla Institute announces 2.0 launch of major database to aid vaccine development worldwide
( La Jolla Institute for Allergy and Immunology ) Key improvements in a major infectious disease database that will aid vaccine development worldwide were unveiled today with the 2.0 launch of the National Institutes of Health-sponsored Immune Epitope Database and Analysis Resource. The 2.0 launch was announced by a research team from the La Jolla Institute for Allergy & Immunology, who ... (Tue, 05 May 2009 19:08:45 GMT)
Agilent Taps Golden Helix to Provide Bioinformatics Support for New CNV Array Line
Golden Helix and Agilent Technologies this week announced that Golden Helix will provide researchers with software tools and services for Agilent’s expanding menu of copy number variation microarrays. (Tue, 05 May 2009 20:48:07 GMT)
In Print
Journal: The Analyst . 2009 Apr;134(4):800-4. Title: Magnetic bead-based DNA hybridization assay with chemiluminescence and chemiluminescent imaging detection. (Tue, 05 May 2009 20:48:18 GMT)
Genome Canada announces results of its Bioproducts and Crops Competition
The Honourable Gary Goodyear, Minister of State (Science and Technology), and Dr. Calvin Stiller, Chairman of the Board of Genome Canada , today announced 12 new genomics and proteomics research projects in the areas of bioproducts and crops. (Tue, 05 May 2009 21:18:34 GMT)
Genomic Health's Q1 Revenues Increase 45 Percent
NEW YORK (GenomeWeb News) – Genomic Health reported after the close of the market on Tuesday that its first-quarter revenues increased 45 percent, while it trimmed its net loss 30 percent. (Tue, 05 May 2009 21:48:15 GMT)
PerkinElmer Buys Analytica
NEW YORK (GenomeWeb News) – PerkinElmer said on Tuesday that it has purchased the mass spectrometry company Analytica of Branford for an undisclosed sum. (Tue, 05 May 2009 21:48:27 GMT)
Life Science Sales, Currency Effects Pull Bio-Rad's Q1 Revenue Down 5 Percent
NEW YORK (GenomeWeb News) – Bio-Rad Laboratories reported after the market close on Tuesday that its first-quarter revenues fell 5 percent on lower life science products sales and the negative effect of foreign currency translation. (Tue, 05 May 2009 22:02:53 GMT)
Blog - New UCSF Chancellor a Boost for Personalized Medicine?
Former Genentech president Susan Desmond-Hellmann is nominated to be the next UCSF chancellor. (Tue, 05 May 2009 22:05:16 GMT)
CDC: Virus-surveillance technology can cut H1N1 flu diagnosis time
A $20 chip can cut the time it takes to distinguish swine flu--aka the H1N1 influenza A virus--from days to hours, the U.S. Centers for Disease Control and Prevention (CDC) said today. [More] (Tue, 05 May 2009 22:21:58 GMT)
Maths Conference At UBD In June
The June 8 to 11 conference focuses on mathematical modelling and computation, together and other aspects of industrial and applied mathematics. The combined MMC09/EASIAM5 conference to be held at UBD's Chancellor Hall will discuss the latest developments in applied maths and math modelling. (Wed, 06 May 2009 02:06:52 GMT)
Ocimum Biosolutions B.V. introduces Affymetrix services in Europe
IJsselstein, May 5 (Business Wire India): In line with its strategic objective to build a global network of service centers in close proximity to leading genomics researchers, Ocimum Biosolutions B.V. today announced the launch of genomic services on Affymetrix platform from Europe. (Wed, 06 May 2009 04:19:09 GMT)
FIZ Karlsruhe now markets in-house version of USGENE®, the USPTO Genetic Sequences Database, in Europe
Agreement gives FIZ Karlsruhe the mandate to operate as SequenceBase Corporation's marketing agent for USGENE® in-house version / USGENE® data available for customized subscription download / expert customer support Karlsruhe, Germany / Edison, NJ, USA, May 2009 - For the purpose of promoting the USGENE® in-house version more effectively in Europe, US-based SequenceBase Corporation and FIZ ... (Wed, 06 May 2009 09:27:29 GMT)
Illumina Introduces Breakthrough Software Advancements with Genome AnalyzerIIx Sequencing System
SAN DIEGO----Illumina, Inc. today announced breakthrough software advancements for its sequencing platform that enable real time analysis and provide a significant reduction in computing infrastructure requirements. (Wed, 06 May 2009 10:00:00 GMT)
Breast Health Center Gives TGen New Research Opportunities
The opening of a new breast health center next to John C. Lincoln Deer Valley Hospital will provide significant research opportunities for the Translational Genomics Research Institute (TGen). (Wed, 06 May 2009 10:20:23 GMT)
Illumina to Present at Upcoming Investment Conferences in May
SAN DIEGO----Illumina, Inc. today announced that the Company will webcast its presentations at two upcoming investment conferences. (Wed, 06 May 2009 10:30:00 GMT)
Novel Gene Predicts Local Recurrence In Early-Onset Breast Cancer
A newly discovered gene known as DEAR1 is mutated in breast cancer and is an independent predictor of local recurrence-free survival in early-onset breast cancer, a research team headed by scientists at The University of Texas M. D. Anderson Cancer Center reports in the journal PLoS Medicine. (Wed, 06 May 2009 11:19:53 GMT)
Aspera Enterprise Server Awarded Best of Show at Bio-IT Awards
EMERYVILLE, Calif.----Aspera, creators of next-generation software technologies that move the world's digital assets at maximum speed regardless of file size, transfer distance or network conditions, was awarded the Best of Show Award for its Aspera Enterprise Server in the IT Infrastructure category at the recent Bio-IT World Conference & Expo in Boston. (Wed, 06 May 2009 12:00:00 GMT)
SRI International Receives $100,000 Grand Challenges Explorations Grant for Innovative Global Health Research by ...
SRI International announced today that it has received a US$100,000 Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation. The grant will support an innovative global health research project conducted by Krishna Kodukula, Ph.D., executive director of SRI International's Center for Advanced Drug Research in Shenandoah Valley, Virginia and Amit Galande, Ph.D., associate ... (Wed, 06 May 2009 13:00:00 GMT)
SRI International receives $100,000 Grand Challenges Explorations grant
( SRI International ) SRI International announced today that it has received a US$100,000 Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation. (Wed, 06 May 2009 13:08:42 GMT)
Researchers Find Gene For Rare Anemia; Discover Surprising Function In Haemoglobin Process Along The Way
Nature Genetics reported an important novel gene discovery by the Dalhousie University-based team of the Atlantic Medical Genetics and Genomics Initiative (AMGGI). The gene, SLC25A38, is associated with a rare form of severe anemia called congenital sideroblastic anemia (CSA). (Wed, 06 May 2009 13:17:32 GMT)
QIAGEN to Present At Baird's 2009 Growth Stock Conference
VENLO, The Netherlands, May 6, 2009 -- QIAGEN N.V. today announced that it will present at Baird's 2009 Growth Stock Conference at 1:55 p.m. CDT on Wednesday, May 12, 2009. The conference is being held at the Four Seasons Hotel in Chicago, Illinois. (Wed, 06 May 2009 13:39:17 GMT)
SRI International Receives $100,000 Grand Challenges Explorations Grant for Innovative Global Health Research by ...
MENLO PARK, CA--(Marketwire - May 6, 2009) - SRI International announced today that it has received a US$100,000 Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation. The grant will support an innovative global health research project conducted by Krishna Kodukula, Ph.D., executive director of SRI International's Center for Advanced Drug Research (CADRE) in Shenandoah ... (Wed, 06 May 2009 13:43:57 GMT)
Recent Patents of Interest in Proteomics
US Patent 7,528,366. Method and apparatus for multiplexing plural ion beams to a mass spectrometer . Inventors: James G Boyle; Robert A Valley. Assignee: Analytica of Branford (Wed, 06 May 2009 14:48:14 GMT)
If GWAS Made You Wary, Be Careful with Social Networking
In much the way scientists learned they could use minimal genotype data to identify "anonymized" individuals from pooled DNA samples, researchers have now determined that it is possible to ID anonymous users of social networking sites , according to this Technology Review article. (Wed, 06 May 2009 15:18:34 GMT)
Researchers Develop Whole Genome Sequencing Approach for Mutation Discovery
The Stowers Institute’s Hawley Lab and Molecular Biology Facility have developed a “whole-genome sequencing approach” to mapping mutations in fruit flies. The novel methodology promises to reduce the time and effort required to identify mutations of biological interest. (Wed, 06 May 2009 15:30:42 GMT)
Novel Gene Shows Local Recurrence In Early-Onset Breast Cancer
A newly discovered gene known as DEAR1 is mutated in breast cancer and is an independent predictor of local recurrence-free survival in early-onset breast cancer, a research team headed by scientists at The University of Texas M. D. (Wed, 06 May 2009 15:43:58 GMT)
Launch Of Major Database To Aid Vaccine Development Worldwide Database To Assist Researchers Around The Globe in ...
Database to assist researchers around the globe in combating infectious diseaseKey improvements in a major infectious disease database that will aid vaccine development worldwide were unveiled today with the 2.0 launch of the National Institutes of Health-sponsored Immune Epitope Database and Analysis Resource (IEDB). (Wed, 06 May 2009 15:45:38 GMT)
This Week in Genome Biology
In Genome Biology this week, scientists at the University of Rochester studied the evolution of R1 and R2 retrotransposons across 12 Drosophila genomes. These specifically insert into the 28S rRNA genes. (Wed, 06 May 2009 15:48:18 GMT)
Database To Assist Researchers Around The Globe In Combating Infectious Disease
Key improvements in a major infectious disease database that will aid vaccine development worldwide were unveiled today with the 2.0 launch of the National Institutes of Health-sponsored Immune Epitope Database and Analysis Resource (IEDB). The 2. (Wed, 06 May 2009 16:05:40 GMT)
Why screening your genes is big business
If you want to peer inside your DNA, there's no shortage of companies offering avenues for doing so these days. (Wed, 06 May 2009 16:10:35 GMT)
IP Update
According the patent's abstract, the invention "relates to compositions and methods for modulating the expression of apolipoprotein B, and more particularly to the down-regulation of apolipoprotein B by chemically modified oligonucleotides." (Wed, 06 May 2009 16:18:04 GMT)
Tech Transfer Tidbits
The John Wayne Cancer Institute at Saint John's Health Center, the National Institutes of Health, and Children's Hospital Los Angeles have granted Texas biotech CerRx worldwide exclusive rights to intellectual property and know-how related to a formulation of vitamin A to treat cancer, JWCI said last week. (Wed, 06 May 2009 16:32:58 GMT)
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