Bioinformatics News Jul 2008: bioinformatics, genomics, proteomics, microarray, etc.

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Migraine Mutations Reveal Clues To Biological Basis Of Disorder
By studying a rare, inherited form of migraine, researchers at Vanderbilt University Medical Center have found clues to the biological basis of the painful, debilitating disorder. (Tue, 01 Jul 2008 03:22:52 GMT)

New Electrostatic-based DNA Microarray Technique Could Revolutionize Medical Diagnostics
Researchers have invented a technique in which DNA assays -- the key to personalized medicine -- can be read and evaluated with no need of elaborate chemical labeling or sophisticated instrumentation. Based on electrostatic repulsion that yields images visible to the naked eye, the technique could revolutionize the use of DNA microarrays for both research and diagnostics. (Tue, 01 Jul 2008 03:23:02 GMT)

QIAGEN Acquires Corbett Life Science
VENLO, The Netherlands, July 1, 2008 -- QIAGEN N.V. today announced that it has acquired Corbett Life Science Pty. Ltd. , a privately-held developer, manufacturer, and distributor of life sciences instrumentation headquartered in Sydney, Australia. (Tue, 01 Jul 2008 06:00:00 GMT)

QIAGEN Acquires Corbett Life Science
Transaction Adds Proprietary Real-Time PCR Detection Technologies to QIAGEN's Portfolio of Molecular Testing Solutions (Tue, 01 Jul 2008 06:54:48 GMT)

01.07.2008 - DJ HUGIN NEWS/QIAGEN Acquires Corbett Life Science
Corporate news announcement processed and transmitted by Hugin ASA. The issuer is solely responsible for the content of this announcement. =----------------------------- =------------- (Tue, 01 Jul 2008 07:05:49 GMT)

Clinical Data Secures EU Patent For MDR1 - A Key Multi-Drug Resistance Gene
Clinical Data, Inc. (NASDAQ: CLDA), a leader in the development of targeted therapeutics and predictive tests from its growing portfolio of proprietary genetic biomarkers, announced today that the European Patent Office has granted Patent No. (Tue, 01 Jul 2008 08:17:53 GMT)

Migraine Mutations Reveal Clues To Biological Basis Of Disorder
Fifteen percent to 20 percent of people worldwide suffer from migraines excruciating headaches often presaged by dramatic sensations, or "auras." By studying a rare, inherited form of migraine, researchers at Vanderbilt University Medical Center have found clues to the biological basis of the painful, debilitating disorder. (Tue, 01 Jul 2008 09:18:43 GMT)

SIRS-Lab Pre-Announces Biomarker Based Sepsis Test
JENA, Germany----SIRS-Lab introduces a new diagnostic concept for the early prediction and reliable monitoring of sepsis. The molecular diagnostic test “SIQNATURE” delivers the earliest possible information about the potential development of a systemic infection. (Tue, 01 Jul 2008 09:30:00 GMT)

Simple method may revolutionise genetic profiling, disease detection
London, July 1 : Researchers at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) claim to have invented a simple and inexpensive method for reading DNA (or RNA) microarrays within minutes. (Tue, 01 Jul 2008 09:52:05 GMT)

The Wellcome Trust Case Control Consortium (WTCCC) Selects Illumina Infinium High-Density (HD) DNA Analysis Products ...
SAN DIEGO----Illumina, Inc. today announced that researchers participating in a new initiative funded by the Wellcome Trust selected Illumina's Infinium HD BeadChips to analyze 90,000 DNA samples. (Tue, 01 Jul 2008 10:00:00 GMT)

Migraines linked to genetic mutations
Washington, July 1 : Researchers from Vanderbilt University Medical Centre have revealed that migraines might be linked to genetic mutations. (Tue, 01 Jul 2008 10:04:34 GMT)

Ore Pharmaceuticals Files Investigational New Drug Application with FDA
Ore Pharmaceuticals Inc. (NASDAQ:ORXE) announced today that it has filed an investigational new drug (IND) application with the U.S. Food and Drug Administration (FDA) for GL1001, the first clinical-stage inhibitor of the ACE2 enzyme. This orally administered small molecule is being developed primarily for inflammatory bowel disease (IBD). Treatment with GL1001 has decreased several disease ... (Tue, 01 Jul 2008 10:23:18 GMT)

The Wellcome Trust Case Control Consortium (WTCCC) Selects Illumina Infinium High-Density (HD) DNA Analysis Products ...
Illumina, Inc. (NASDAQ:ILMN) today announced that researchers participating in a new initiative funded by the Wellcome Trust selected Illumina's Infinium HD BeadChips to analyze 90,000 DNA samples. This new initiative aims to decipher the molecular basis of human disease and includes participation from leading research groups around the globe. Together, researchers at the Wellcome Trust Case ... (Tue, 01 Jul 2008 10:23:38 GMT)

Duke offers free health seminars in Kannapolis
By Emily Ford eford@salisburypost.com KANNAPOLIS — Residents will meet the scientists who will study this city for the next several years when Duke ... (Tue, 01 Jul 2008 10:31:31 GMT)

The Wellcome Trust Case Control Consortium (WTCCC) Selects Illumina Infinium High-Density (HD) DNA Analysis Products ...
The Wellcome Trust Case Control Consortium (WTCCC) Selects Illumina Infinium High-Density (HD) DNA Analysis Products to Study 90,000 Samples (Tue, 01 Jul 2008 10:54:04 GMT)

New DNA Microarray Technique Based on Electrostatics
Detecting specific genes and pathogens in DNA and RNA is typically quite expensive and time consuming. But that's about to change.... (Tue, 01 Jul 2008 11:41:45 GMT)

State officially launches the ECMC-Kaleida consolidation
The state signed on Monday as an enthusiastic supporter of the plan to combine Kaleida Health and Erie County Medical Center under one administration, with Dr. Richard F. Daines, state health commissioner, the top cheerleader. (Tue, 01 Jul 2008 12:17:54 GMT)

Researchers Are First To Simulate The Binding Of Molecules To A Protein
You may not know what it is, but you burn more than your body weight of it every day. Adenosine triphosphate (ATP), a tiny molecule that packs a powerful punch, is the primary energy source for most of your cellular functions. Now researchers at the University of Illinois have identified a key step in the cellular recycling of ATP that allows your body to produce enough of it to survive. (Tue, 01 Jul 2008 12:18:33 GMT)

Pacific Rim Summit Will Showcase Advanced Biotech Tools for Renewable Fuels and Chemicals
At Pacific Rim Summit, scheduled for Sept 10-12 in Vancouver, research scientists and industry leaders will present progress in developing advanced biotech fuels and chemicals through genomics, synthetic biology, and genetic engineering. Scheduled plenary speaker, Drew Endy, Assistant Professor of Bioengineering at Stanford University, will discuss how new understanding of genomic information is ... (Tue, 01 Jul 2008 12:46:22 GMT)

Hybrigenics And Dualsystems Enter Into Strategic Partnership For Yeast Two-Hybrid Screens Of Full Membrane Proteins
Hybrigenics, a listed bio-pharmaceutical company with a focus on research and development of new cancer treatments and specialized in protein interactions, announced that it has formed a strategic partnership to complement Hybrigenics' portfolio with Dualsystems' DUALmembrane yeast two-hybrid technology especially designed for full membrane proteins (Tue, 01 Jul 2008 13:02:56 GMT)

Supercomputer Used To Track Pathways In Myoglobin
Some 50 years ago, after decades of effort, John Kendrew determined the structure of the small globular protein, myoglobin, which is responsible for oxygen storage in cells. For this discovery, he shared the Nobel Prize in chemistry with Max Perutz, who did similar work on hemoglobin. (Tue, 01 Jul 2008 13:17:33 GMT)

BioTrove, Gene Express Awarded NIH Grant to Develop Novel Standardized Genetic Profiling Test
BioTrove, Inc. and Gene Express, Inc. today announced their receipt of a two-year National Institutes of Health (NIH) grant, awarded in support of their proposed novel research of genetic biomarkers for lung cancer. Part of the NIH competitive grant program "Innovative Technologies for Molecular Analysis of Cancer," the project will combine for the first time BioTrove's OpenArray(TM) nanofluidic ... (Tue, 01 Jul 2008 14:10:19 GMT)

Medical Diagnostics Could Be Revolutionized By New Electrostatic-Based DNA Microarray Technique
The dream of personalized medicine - in which diagnostics, risk predictions and treatment decisions are based on a patient's genetic profile - may be on the verge of being expanded beyond the wealthiest of nations with state-of-the-art clinics. A team of researchers with the U.S. (Tue, 01 Jul 2008 14:17:13 GMT)

Celera makes split official, moves to California
Celera Corp. has separated from its parent company and ended its run as a high-flying local biotech. (CRA) (Tue, 01 Jul 2008 14:53:16 GMT)

Celera makes split official, moves to California
Celera Corp. has separated from its parent company and ended its run as a high-flying local biotechnology firm. (CRA) (OFC) (Tue, 01 Jul 2008 15:38:03 GMT)

IBT Laboratories Names Maureen Loftus President and Chief Operating Officer
IBT Laboratories, a leading global clinical-diagnostics and biomedical-research laboratory specializing in immunology and allergy assays, announced that Maureen Loftus has joined the company as president and chief operating officer. (Tue, 01 Jul 2008 16:03:00 GMT)

Genomics Research Focuses on Rice Variety Improvement
Crop varieties can be improved through the study of genomics without creating genetically transformed varieties. That is the mission of a multistate research project led by the University of Arkansas System`s Division of Agriculture. (Tue, 01 Jul 2008 18:07:31 GMT)

Pediatric researchers find possible 'master switch' gene in juvenile arthritis
PHILADELPHIA, July 1, 2008 – Researchers have found that a gene region known to play a role in some varieties of adult rheumatoid arthritis is also present in all types of childhood arthritis. (Tue, 01 Jul 2008 18:41:49 GMT)

Fungi the cause of many outbreaks of disease but mostly ignored
There is a serious lack of scientific data to support any stance with respect to indoor mold toxicity or remediation. More effort should be devoted to testing and long-term monitoring of mold contamination and human health in New Orleans and other areas flooded by Hurricane Katrina. (Tue, 01 Jul 2008 18:56:49 GMT)

Frontiers in Psychiatric Research
These are exciting times for genetics research: Science magazine chose our new appreciation of human genetic diversity as the scientific breakthrough of the year 2007. 1 The year brought a new genetic bonanza with the announcement of the 1000 Genome Project, a plan to capture human diversity by obtaining the entire genome sequence information of 1000 individuals. (Tue, 01 Jul 2008 23:51:43 GMT)

Addiction Research and Treatment
The nation's leading causes of death are related to alcohol and drug use, tobacco smoke exposure, and behavioral addictions. Each year, more than 400,000 Americans die as a result of smoking, overeating, substance use, and related accidents and suicide. (Tue, 01 Jul 2008 23:51:51 GMT)

Designer diet for prostate cancer
For the first time, a research group at the Institute of Food Research led by Professor Richard Mithen has provided an explanation of how eating broccoli might reduce cancer risk based upon studies in men, as opposed to trying to extrapolate from animal models. Prostate cancer is the most common non-skin cancer for males in western countries. The research has provided an insight into why eating ... (Wed, 02 Jul 2008 00:11:51 GMT)

Designer diet for prostate cancer
Eating one or more portions of broccoli every week can reduce the risk of prostate cancer, and the risk of localised cancer becoming more aggressive. (Wed, 02 Jul 2008 00:16:05 GMT)

BioWorld International Correspondent
BRUSSELS, Belgium - There is a slowdown in the volume of useful new drugs on the European market, and biotech is in part to blame, according to the leading European pharmaceutical industry association. (Wed, 02 Jul 2008 00:28:09 GMT)

Waters India to tap proteomics research prospects with its package of solutions
Waters India is now is aggressively pursuing opportunities to expand its proteomics business in the country. (Wed, 02 Jul 2008 02:38:38 GMT)

Footrot vaccine closer than ever
Monash University scientists have started clinical trials to find a successful vaccine against footrot in sheep. (Wed, 02 Jul 2008 04:11:51 GMT)

DNA Technology Posts Exponential Speed Increases
A prominent genetics research facility, the Wellcome Trust Sanger Institute, recently sequenced its trillionth base pair of DNA, illustrating the exponential increases in speed that new DNA sequencers have made possible. (Wed, 02 Jul 2008 04:31:21 GMT)

Search begins for new UA vice president
The medical school's dean is set to resign. (Wed, 02 Jul 2008 06:52:19 GMT)

Sequenom Launches iSEQ Application
SAN DIEGO----Sequenom, Inc. , a leading provider of genetic analysis solutions, today announced the launch of the iSEQ™ application software, a MassARRAY® comparative sequence analysis application for automated, high-throughput identification and typing of microbes and viruses, as well as human disease-related molecular markers. (Wed, 02 Jul 2008 08:00:00 GMT)

Sequenom Launches iSEQ Application
Sequenom, Inc. (NASDAQ: SQNM), a leading provider of genetic analysis solutions, today announced the launch of the iSEQ(TM) application software, a MassARRAY(R) comparative sequence analysis application for automated, high-throughput identification and typing of microbes and viruses, as well as human disease-related molecular markers. This product is directed toward the infectious disease market ... (Wed, 02 Jul 2008 08:23:08 GMT)

New High-Tech Imaging Center "TIGA" At The University Of Heidelberg / Robot "NanoZoomer" Shows High-Resolution Images ...
"TIGA," the new high-tech imaging center at the University of Heidelberg founded in cooperation with the Japanese company Hamamatsu, provides deep insights: a high-tech robot makes it possible for the first time to automatically reproduce and evaluate tissue slices only micromillimeters thick - an im (Wed, 02 Jul 2008 09:17:33 GMT)

Massachusettsfirm purchases Open Biosystems
Open Biosystems, one of Huntsville's leading biotechnology companies, has been acquired by Thermo Fisher Scientific in Massachusetts. Open Biosystems, based at the HudsonAlpha Institute for Biotechnology, produces genomic research tools. (Wed, 02 Jul 2008 09:21:35 GMT)

Eating broccoli can reduce prostate cancer risk
Washington, July 2 : Eating a broccoli-rich diet can reduce the risk of deadly prostate cancer, according to researchers. (Wed, 02 Jul 2008 09:41:57 GMT)

Footrot vaccine closer than ever
Monash University scientists have started clinical trials to find a successful vaccine against footrot in sheep. (Wed, 02 Jul 2008 09:52:11 GMT)

Relaxation response can influence expression of stress-related genes
How could a single, nonpharmacological intervention help patients deal with disorders ranging from high blood pressure, to pain syndromes, to infertility, to rheumatoid arthritis? That question may have been answered by a study finding that eliciting the relaxation response - a physiologic state of deep rest - influences the activation patterns of genes associated with the body's response to ... (Wed, 02 Jul 2008 09:52:22 GMT)

Eating broccoli can reduce cancer risk 2 Jul 2008, 1546 hrs IST,ANI
WASHINGTON: Eating a broccoli-rich diet can reduce the risk of deadly prostate cancer, according to researchers. What's more, the consumption of one or more portions of the green veggie can lessen the risk of localized cancer becoming more aggressive. (Wed, 02 Jul 2008 10:33:18 GMT)

VLST Corporation Appoints Internationally Recognized Researcher Paul J. Carter, Ph.D. as Chief Scientific Officer
SEATTLE----VLST Corporation, a Seattle-based biotechnology company focused on the development of therapeutics for autoimmune and inflammatory disorders, today announced that Paul J. (Wed, 02 Jul 2008 12:00:00 GMT)

VLST Corporation Appoints Internationally Recognized Researcher Paul J. Carter, Ph.D. as Chief Scientific Officer
VLST Corporation, a Seattle-based biotechnology company focused on the development of therapeutics for autoimmune and inflammatory disorders, today announced that Paul J. Carter, Ph.D., a 20-year biotechnology research veteran, will join the Company as chief scientific officer and senior vice president of research and development. (Wed, 02 Jul 2008 12:39:08 GMT)

Footrot Vaccine For Sheep Closer Than Ever
Scientists have started clinical trials to find a successful vaccine against footrot in sheep. (Wed, 02 Jul 2008 13:09:59 GMT)

Ore Pharmaceuticals files to test drug on humans
Ore Pharmaceuticals Inc. has filed an application to begin testing its first drug compound in humans. (ORXE) (Wed, 02 Jul 2008 13:10:50 GMT)

Eating Broccoli May Keep Prostate Cancer Away, Study Suggests
For the first time, a research group has provided an explanation of how eating broccoli might reduce cancer risk based upon studies in men, as opposed to trying to extrapolate from animal models. Prostate cancer is the most common non-skin cancer for males in western countries. The research has provided an insight into why eating broccoli can help men stay healthy. (Wed, 02 Jul 2008 14:12:49 GMT)

Healthy Or Diseased? Analysis Of Body's Metabolism Sheds New Light On The Question
Scientists have shown that biological indicators for diseases caused or influenced by environmental factors can be detected by the systemic analysis of the body's metabolism (metabolomics). The procedure presented here is also suitable for pre-clinical drug testing and allows for the early detection of possible side effects of a new medication. (Wed, 02 Jul 2008 15:24:58 GMT)

Professor Pevzner’s Do-It-Yourself Proteomics Class
Budding bioinformaticists in Pavel Pevzner’s undergraduate research experiences class looked at the proteins found in a bacterium and worked backward to identify the genes that created them. (Wed, 02 Jul 2008 16:04:07 GMT)

How relaxation response helps you deal with high BP, infertility and more
Washington, July 2 : A collaborative study by members of the Benson-Henry Institute for Mind/Body Medicine at Massachusetts General Hospital (MGH) and the Genomics Center at Beth Israel Deaconess Medical Center (BIDMC) casts light on how the relaxation response, a physiologic state of deep rest, enables patients to deal with disorders like high blood pressure, pain syndromes, infertility, ... (Wed, 02 Jul 2008 16:06:26 GMT)

UC San Diego undergraduates forge new area of bioinformatics
A screen shot of some of the bioinformatics software that undergraduate students from the University of California San Diego created during their quest to forge a new area of... (Wed, 02 Jul 2008 16:06:38 GMT)

BioScience tip sheet July/August 2008
High-Speed Developments in Avian Genomics. Camille Bonneaud, Joan Burnside, and Scott V. Edwards. (Wed, 02 Jul 2008 16:15:32 GMT)

Sequencing at the Speed of Lightning
The technology for genome sequencing is advancing and costing less, giving rise to a flood of innovation. (Wed, 02 Jul 2008 17:00:00 GMT)

Undergraduates Forge New Area Of Bioinformatics
A group of undergraduate students have forged a new area of bioinformatics that may improve genomic and proteomic annotations and unlock a collection of stubborn biological mysteries. Their work will be published in the journal Genome Research. (Wed, 02 Jul 2008 17:10:41 GMT)

New Senate majority leader starts upstate tour today in Buffalo
The man responsible for protecting the Republican majority in the State Senate visited Buffalo today for meetings with the mayor and Erie County executive and to assure local leaders he has an ear to upstate. (Wed, 02 Jul 2008 17:17:14 GMT)

National cancer experts meet in Louisville to discuss future of cancer care
A panel of national cancer experts today discussed issues surrounding the disease during a symposium entitled "Discovery to Delivery: A Public Forum about the Future of Cancer Research." (Wed, 02 Jul 2008 18:07:12 GMT)

Pediatric Researchers Find Possible 'Master Switch' Gene In Juvenile Arthritis
Researchers have found that a gene region known to play a role in some varieties of adult rheumatoid arthritis is also present in all types of childhood arthritis. The researchers say the responsible gene may be a "master switch" that helps turn on the debilitating disease. (Wed, 02 Jul 2008 21:10:39 GMT)

Relaxation Response Can Influence Expression Of Stress-related Genes
How could a single, non-pharmacological intervention help patients deal with disorders ranging from high blood pressure, to pain syndromes, to infertility, to rheumatoid arthritis? That question may have been answered by a study finding that eliciting the relaxation response -- a physiologic state of deep rest -- influences the activation patterns of genes associated with the body's response to ... (Wed, 02 Jul 2008 21:11:19 GMT)

Evolutionary Origin Of Mammalian Gene Regulation Is Over 150 Million Years Old
Scientists have found that a complex, highly conserved and extremely important mechanism of controlling genes is over 150 million years old. The findings have provided new insights into the evolution of genomic or parental imprinting and epigenetic regulation in mammals. A failure of these sophisticated processes is associated with many human genetic diseases, psychiatric and autoimmune ... (Wed, 02 Jul 2008 21:11:49 GMT)

Sen. Clinton returns to Buffalo's inner harbor
Buffalo, N.Y. (WIVB) - - New York's Junior U.S. Senator is back in Buffalo for the first time in about a year. (Wed, 02 Jul 2008 22:04:59 GMT)

Yoga And Meditation Change Gene Response To Stress
Research from the US suggests that mind body techniques like yoga and meditation that put the body in a state of deep rest known as the relaxation response, are capable of changing how genes behave in response to stress. (Wed, 02 Jul 2008 22:16:12 GMT)

End of an era: Celera moves its HQ to California
Celera Corp., which helped put Maryland’s biotechnology sector on the map with its role in sequencing the human genome, has split from its parent company and relocated its headquarters to California. (Wed, 02 Jul 2008 23:27:56 GMT)

Linked by Thom Holwerda on Mon 6th Feb 2006 22:21 UTC, submitted by Anonymous Goatherd
"Apple wants to make their switch to Intel chips seem like a no-brainer, but the reality of it was a lot more complicated than just faster chips for Macs. Apple's claims of their Intel systems being '4-5x faster' than their PowerPC systems is a little much to swallow, especially with Intel Macs landing in users' hands and failing to live up to the hype. (Thu, 03 Jul 2008 01:03:34 GMT)

Genetic Study Supports Mind/Body Connection
By Rick Nauert, Ph.D. Psych Central - A collaborative investigation demonstrates how a single, nonpharmacological intervention can help patients deal with disparate medical disorders. (Thu, 03 Jul 2008 08:33:37 GMT)

Indian scientists developing drought-resistant groundnut
Indian farmers will soon get access to a new variety of groundnut that is drought-resistant and can be cultivated even in areas where water is scarce. (Thu, 03 Jul 2008 08:40:01 GMT)

Online genetic testing exposed as a scam
SENDING YOUR BODIL Y fluids off to online DNA testing centres probably won’t bring you any closer to solving the mysteries in your family tree, according to an undercover investigation. (Thu, 03 Jul 2008 09:18:23 GMT)

Antigen Discovery Inc. Awarded a SBIR Phase II Grant to Commercialize Novel Antigens for Serodiagnostic Products and ...
Antigen Discovery Inc. , a leader in high throughput antigen/biomarker discovery using advanced genomics and proteomics tools, announced today that the Company was awarded a Phase II SBIR from the National Institute of Allergy and Infectious Diseases and the National Center for Research Resources . (Thu, 03 Jul 2008 10:00:00 GMT)

Beijing Genomics Institute signs global site license with CLC bio for Next Generation Sequencing software platform
Beijing Genomics Institute (BGI) has signed a global site license agreement for CLC bio's Next Generation Sequencing solution, CLC Genomics Workbench. The site license covers all researchers at all BGI sites, both inside and outside of China. [Wired by: PressReleaseNetwork.com] (Thu, 03 Jul 2008 10:49:00 GMT)

Yoga, meditation improve health by switching off stress genes
Washington, July 3 : Scientists have achieved a significant breakthrough in understanding how relaxation techniques like yoga, meditation, and prayer improve health. (Thu, 03 Jul 2008 10:52:29 GMT)

HapMap Browsing And DDDP Methods For Genetic Analysis Featured In CSH Protocols
To aid in the study of genetic diseases, scientists with the International Haplotype Map Project have developed a haplotype map of the human genome, a tool that displays common patterns of genetic variation. While data from the project are available for unrestricted public use from the project's website (http://www.hapmap. (Thu, 03 Jul 2008 11:18:32 GMT)

Metabolomics Sheds New Light On The Question "Healthy Or Diseased?"
Metabolomics aims to determine the totality of all small molecules of a cell or a tissue. The exponents of bioinformatics analyzed data collected in the framework of a pre-clinical metabolomics study in healthy and diabetic mice. In each case, a subgroup of the animals was treated with the diabetes drug RoziglitazoneTM. (Thu, 03 Jul 2008 12:17:04 GMT)

Affymetrix Technology Used To Discover Molecular Mechanisms Of Liver Disease
Affymetrix Inc. (Nasdaq:AFFX) announced that a team of researchers at the Fraunhofer Institute in Germany is using Affymetrix' Whole Transcript (WT) gene expression technology to better understand the molecular basis of drug-induced liver injury (DILI). (Thu, 03 Jul 2008 12:18:25 GMT)

KU Researcher Calls for Approval of Wireless Gadgets That Use 'White Space'
In most regions of the country, ample swaths of the television spectrum go unused. Such "white space" in the TV band once comprised useful buffer zones between broadcasters that cut the risk of interference, the way medians divide highway lanes. But research at the University of Kansas shows that the digital revolution has lifted the need for unoccupied gaps in the TV spectrum and opened white ... (Thu, 03 Jul 2008 12:23:44 GMT)

Rosetta Genomics to Present at Collins Stewart Fourth Annual Growth Conference
Rosetta Genomics Ltd , a leading developer of microRNA-based diagnostics and therapeutics, announced today it will present Collins Stewart Fourth Annual Growth Conference on Wednesday, July 9, at 8:30 am EST at the Mandarin Oriental Hotel in New York. (Thu, 03 Jul 2008 12:30:00 GMT)

Connectomics: Mapping the Nervous System [60-Second Science]
[The following is an exact transcript of this podcast.] It took 13 years and countless hours of research to unravel the human genome. Now neuroscientists want to do their field’s version. A small group of researchers is advancing the emerging field of what they call “connectomics.” As genomics moved from individual genes to the entire genome, so connectomics wants to take us from individual ... (Thu, 03 Jul 2008 13:07:54 GMT)

The Wellcome Trust Case Control Consortium (WTCCC) Selects Illumina Infinium High-Density (HD) DNA Analysis Products ...
Illumina, Inc. (NASDAQ:ILMN) announced that researchers participating in a new initiative funded by the Wellcome Trust selected Illumina's Infinium HD BeadChips to analyze 90,000 DNA samples. This new initiative aims to decipher the molecular basis of human disease and includes participation from leading research groups around the globe. (Thu, 03 Jul 2008 13:18:54 GMT)

UC San Diego Undergraduates Forge New Area Of Bioinformatics
A group of undergraduate students from the University of California San Diego have forged a new area of bioinformatics that may improve genomic and proteomic annotations and unlock a collection of stubborn biological mysteries. Their work will be published in the July issue of the journal Genome Research. (Thu, 03 Jul 2008 13:19:14 GMT)

University of Hawaii researchers discover new pathway for methane production in the oceans
Honolulu, HI – A new pathway for methane production has been uncovered in the oceans, and this has a significant potential impact for the study of greenhouse gas production on our planet. (Thu, 03 Jul 2008 13:25:04 GMT)

Explore the Principles of Computational Cell Biology
DUBLIN, Ireland----Research and Markets has announced the addition of the "Principles of Computational Cell Biology: From Protein Complexes to Cellular Networks" report to their offering. (Thu, 03 Jul 2008 15:01:00 GMT)

Red wine ingredient wards off effects of age on heart, bones, eyes and muscle
Large doses of a red wine ingredient can ward off many of the vagaries of aging in mice who begin taking it at midlife, according to a new report published online on July 3rd in Cell Metabolism , a Cell Press publication. (Thu, 03 Jul 2008 16:08:18 GMT)

New Pathway For Methane Production In The Oceans Discovered
A new pathway for methane production has been uncovered in the oceans, and this has a significant potential impact for the study of greenhouse gas production on our planet. The article reveals that aerobic decomposition of an organic, phosphorus-containing compound, methylphosphonate, may be responsible for the supersaturation of methane in ocean surface waters. (Thu, 03 Jul 2008 16:21:54 GMT)

State approves Kaleida-ECMC consolidation
New York State Health Commissioner Richard F. Daines traveled to Buffalo Monday to announce his department’s approval of the consolidation of the Kaleida Health System and Erie County Medical Center to create the Western New York Healthcare System. (Thu, 03 Jul 2008 16:40:24 GMT)

Cell Biosciences Strengthens Management Team
Cell Biosciences, Inc., a provider of ultrasensitive protein detection and characterization systems to life science researchers, today announced three key management team additions. (Thu, 03 Jul 2008 16:48:00 GMT)

UCLA researchers clarify function of glucose transport molecule
Researchers at the David Geffen School of Medicine at UCLA have solved the structure of a class of proteins known as sodium glucose co-transporters (SGLTs), which pump glucose into cells. (Thu, 03 Jul 2008 20:01:38 GMT)

Researchers Clarify Function of Glucose Transport Molecule; Findings May Lead to Improved Treatments for Diabetes, ...
UCLA scientists have solved the structure of a class of proteins known as sodium glucose co-transporters (SGLTs), which pump glucose into cells. The solution of the SGLT structure will accelerate development of new drugs designed to treat patients with diabetes and cancer. The journal Science publishes the findings. (Thu, 03 Jul 2008 20:22:48 GMT)

Researchers Are First To Simulate The Binding Of Molecules To A Protein
You may not know what it is, but you burn more than your body weight of it every day. Adenosine triphosphate, a tiny molecule that packs a powerful punch, is the primary energy source for most of your cellular functions. Now researchers have identified a key step in the cellular recycling of ATP that allows your body to produce enough of it to survive. (Thu, 03 Jul 2008 22:22:04 GMT)

More News
Celera Corp., the human genome pioneer that helped put Rockville and Maryland on the national biotech map almost a decade ago, has completed its previously announced separation from its parent, Applera Corp., and as of this week is an independent company publicly traded on the Nasdaq. (Fri, 04 Jul 2008 02:15:08 GMT)

Sigmund appointed to research chair
Curt D. Sigmund, professor of internal medicine and molecular physiology and biophysics in the University of Iowa Roy J. and Lucille A. Carver College of Medicine, has been named the Roy J. Carver Chair in Hypertension Research. The five-year appointment was effective July 1. (Fri, 04 Jul 2008 08:32:38 GMT)

Relaxation Response Can Influence Expression Of Stress-Related Genes
How could a single, nonpharmacological intervention help patients deal with disorders ranging from high blood pressure, to pain syndromes, to infertility, to rheumatoid arthritis? That question may have been answered by a study finding that eliciting the relaxation response - a physiologic state of (Fri, 04 Jul 2008 09:06:10 GMT)

New Anti-Keratin Antibodies Introduced by AnaSpec
AnaSpec has introduced two keratin antibodies that recognize both the intact and caspase digested N-terminal of K18 and K19 at Asp237. These antibodies are useful tools for studying keratin dynamics in mice undergoing hepatocyte apoptosis, patients with cirrhosis, and also in apoptotic cells of various epithelial human tumors in a non-invasive manner. Intermediate filaments (IFs), together with ... (Fri, 04 Jul 2008 15:57:03 GMT)

M-Scan Ltd Successfully Passes GMP Inspections by the FDA and UK MHRA
The world-leading provider of contract analytical services now conducts bio/pharmaceutical analysis to both GMP and GLP (compliant since 1992.) [PR.com - July 04, 2008] (Fri, 04 Jul 2008 15:59:24 GMT)

Milken students win first high school X PRIZE
Milken Community High School students joined the space race this week when two seniors won the first-ever X PRIZE competition for high schoolers. (Sat, 05 Jul 2008 00:07:44 GMT)

ADI wins SBIR Phase II grant to commercialize novel antigens
Antigen Discovery has received a Phase II SBIR from the National Institute of Allergy and Infectious Diseases and the National Center for Research Resources. (Sat, 05 Jul 2008 00:31:14 GMT)

Researchers reveal types of genes necessary for brain development
Researchers from Harvard Medical School and Brandeis University have successfully completed a full-genome RNAi screen in neurons, showing what types of genes are necessary for brain development. Details of the screen and its novel methodology are published July 4th in the open-access journal PLoS Genetics. (Sat, 05 Jul 2008 02:13:49 GMT)

Shining a light on genetic testing
Several experts question whether direct-to-consumer tests are valid or accurate. (Sat, 05 Jul 2008 05:29:59 GMT)

Analysis of body's metabolism can tell whether you're healthy
Want to find out whether you are healthy or diseased? An analysis of body's metabolism can give you an answer, says a new study. (Sat, 05 Jul 2008 07:01:20 GMT)

Former Intel Chair Andy Grove: Energizing the Rollout of Plug-In Cars
Former Intel Chairman Andy Grove has a knack for sensing when circumstances should force changes at a company or an industry -- and how to respond. He even has coined a term for it: the "strategic inflection point." Now the retired chairman of the world's largest computer chip maker thinks the term applies to energy and transportation. (Sat, 05 Jul 2008 11:09:23 GMT)

Function Of Glucose Transport Molecule Clarified By UCLA Researchers
Researchers at the David Geffen School of Medicine at UCLA have solved the structure of a class of proteins known as sodium glucose co-transporters (SGLTs), which pump glucose into cells. These transport proteins are used in the treatment of chronic diarrhea via oral rehydration therapy, saving the lives of millions of children each year. (Sat, 05 Jul 2008 14:05:29 GMT)

Dublin, Ireland July 4, 2008 Scientists from all over the world will travel to Ireland in August for the Agricultural ...
(ABIC). Exciting new developments in biotechnology will be presented and discussed over the three-day conference which takes place in University College Cork beginning on Sunday, 24 August 2008. (Sat, 05 Jul 2008 20:07:18 GMT)

In genes, pair sees future of medicine
When West Boca Raton High cheerleader Stephanie Kuleba died in March after outpatient surgery, geneticists Jeffery Vance and Margaret Pericak-Vance had a suspicion. (Sun, 06 Jul 2008 00:47:29 GMT)

Merrimack College turns focus to biotechnology and biomedical sciences
NORTH ANDOVER — The local biotechnology industry is receiving a lot of attention after Gov. Deval Patrick signed a $1 billion bill last month to promote the life sciences industry in Massachusetts. (Sun, 06 Jul 2008 02:59:11 GMT)

Genetics for the average patient
When West Boca Raton High cheerleader Stephanie Kuleba died in March after outpatient surgery, geneticists Jeffery Vance and Margaret Pericak-Vance had a suspicion. (Sun, 06 Jul 2008 07:22:44 GMT)

Researchers Reveal Types Of Genes Necessary For Brain Development
Researchers from Harvard Medical School and Brandeis University have successfully completed a full-genome RNAi screen in neurons, showing what types of genes are necessary for brain development. Details of the screen and its novel methodology are published July 4th in the open-access journal PLoS Genetics. (Sun, 06 Jul 2008 08:08:30 GMT)

Red Wine Ingredient Wards Off Effects Of Age On Heart, Bones, Eyes And Muscle
Large doses of a red wine ingredient can ward off many of the vagaries of aging in mice who begin taking it at midlife, according to a new report published online on July 3rd in Cell Metabolism, a Cell Press publication. (Sun, 06 Jul 2008 12:05:29 GMT)

Outstanding young S’poreans honoured at youth award ceremony
SINGAPORE: Three individuals and two teams received this year’s Singapore Youth Award from Deputy Prime Minister Professor S Jayakumar at the Istana on Sunday. (Sun, 06 Jul 2008 13:23:36 GMT)

Top Scoops
(Draft Version for review...) Will the Real Theory of Evolution Please Stand Up? (Sun, 06 Jul 2008 21:49:19 GMT)

New Head For Food Standards Australia New Zealand
A former Commonwealth Ombudsman, Philippa Smith AM, has been appointed as Chair of the Food Standards Australia New Zealand (FSANZ) board. The Parliamentary Secretary to the Minister for Health and Ageing, Senator Jan McLucas, said today Ms Smith would take up the position for four years. (Mon, 07 Jul 2008 03:49:09 GMT)

The Scientific Business of Thomson Reuters Examines the Hottest U.K. Institutions
The Scientific business of Thomson Reuters today announced results of a study assessing high-impact research by the United Kingdom's top-cited institutions and researchers. In the May/June issue of Science Watch and on ScienceWatch.com, Thomson Reuters analyzes data from its Essential Science Indictors to identify "high-impact papers" that rank among the top one percent most-cited, by field, ... (Mon, 07 Jul 2008 04:01:00 GMT)

Regulation battle will shape future of genomics companies
Navigenics Inc. (Mon, 07 Jul 2008 05:37:23 GMT)

Youths spend summer in science lab
Classmates used to kid Juliet Kasaya when they found out her favorite subject was science. (Mon, 07 Jul 2008 07:06:30 GMT)

Genetic haul lifts hopes on Crohn's
If finding disease-related genes is like fishing, then scientists have recently shifted from rods and reels to big nets, and they have just announced their biggest haul ever. (Mon, 07 Jul 2008 07:23:10 GMT)

Medical advances promising, but hurdles exist
According to presenters at last week’s Aspen Ideas Festival, there is a great deal of hope on the medical front, especially for modern day’s biggest medical bogeymen: Cancer and AIDS. But the barrier to having a world full of healthy people is often not medical expertise, but access to and affordability of medical care. (Mon, 07 Jul 2008 08:26:53 GMT)

AutoGenomics INFINITI Analyzer Receives Artistic Design Award
The Society of Plastics Engineers in their Annual Thermoforming Division Meeting selected the INFINITI Analyzer from AutoGenomics as a recipient of the artistic Multi-Part design award. (Mon, 07 Jul 2008 10:00:00 GMT)

Agios Pharmaceuticals Closes $33 Million Series A Funding
CAMBRIDGE, Mass.----Agios Pharmaceuticals, the first biopharmaceutical company focused on discovering and developing novel drugs that target key metabolic pathways to fundamentally disrupt cancer cells' ability to grow and survive, today announced that it has closed a $33 million Series A financing. (Mon, 07 Jul 2008 12:00:00 GMT)

Learn about the World Biotechnology Instrumentation Market
Reportlinker.com announces that a new market research report related to the Medical devices industry is available in its catalogue. (Mon, 07 Jul 2008 12:43:00 GMT)

Review article provides tools for the Rosaceae genomics community
The woodland strawberry, a member of the Rosaceae family. (Mon, 07 Jul 2008 13:08:25 GMT)

The Energy Superbugs
Extremophiles create, collect and store power in ways once reserved to the realm of comic book superheroes. Can they teach us how it's done? (Mon, 07 Jul 2008 13:08:51 GMT)

Review article provides tools for the Rosaceae genomics community
A recent paper published in the journal Plant Physiology provides a comprehensive overview of the genomics tools and resources available for the rapidly growing Rosaceae scientific community. Rosaceae is an economically important group of plants that comprises more than 3,000 species, including strawberry, apple, peach and pear. Members of this plant family provide high-value nutritional foods ... (Mon, 07 Jul 2008 13:49:23 GMT)

Frost & Sullivan Recognizes Iris BioTechnologies for Technology Innovation in the Pharmacogenomics Arena
PALO ALTO, Calif.----Based on its recent analysis of the pharmacogenomics market, Frost & Sullivan presents Iris BioTechnologies Inc. with the 2008 North American Frost & Sullivan Award for Technology Innovation. (Mon, 07 Jul 2008 14:12:00 GMT)

Review Of Tools For Genomics Community Studying Rosaceae (Apple, Peach, Pear, Strawberry)
A comprehensive overview of the genomics tools and resources available for the rapidly growing Rosaceae scientific community has been published. Rosaceae is an economically important group of plants that comprises more than 3,000 species, including strawberry, apple, peach and pear. (Mon, 07 Jul 2008 14:21:45 GMT)

Frost & Sullivan Recognizes Iris BioTechnologies for Technology Innovation in the Pharmacogenomics Arena
Based on its recent analysis of the pharmacogenomics market, Frost & Sullivan presents Iris BioTechnologies Inc. (Iris) with the 2008 North American Frost & Sullivan Award for Technology Innovation. The Award recognizes the firm's remarkable efforts toward the development of a patented, integrated technology platform, the Nano-Biochip(TM) gene expression diagnostic system and an artificial ... (Mon, 07 Jul 2008 14:29:04 GMT)

OMEGA Multi-Conformer Databases Now Compatible with MOE
SANTA FE, N.M. & MONTREAL----OpenEye Scientific Software, Inc., the developer of innovative molecular modeling and cheminformatics solutions for drug discovery, and Chemical Computing Group, Inc., a leading supplier of scientific software for Life Sciences, announced today the release of a utility allowing OMEGA conformer databases in OpenEye binary format to be converted into a MOE compatible ... (Mon, 07 Jul 2008 14:32:00 GMT)

Embryo Viability Studies Support Utility Of Novel, Metabolomic Profiling Technology
Molecular Biometrics, LLC, a privately-held metabolomics company developing novel clinical tools for applications in personalized medicine to more accurately characterize biologic function in health and disease, presented data from four new studies evaluating the benefits of metabolomic profiling to determine embryo viability and enhance in vitro fertilization (IVF) outcomes (Mon, 07 Jul 2008 14:36:51 GMT)

OMEGA Multi-Conformer Databases Now Compatible with MOE
OpenEye Scientific Software, Inc., the developer of innovative molecular modeling and cheminformatics solutions for drug discovery, and Chemical Computing Group, Inc., a leading supplier of scientific software for Life Sciences, announced today the release of a utility allowing OMEGA conformer databases in OpenEye binary (oeb) format to be converted into a MOE compatible multi-conformer file. (Mon, 07 Jul 2008 14:58:01 GMT)

Researchers Clarify Function Of Glucose Transport Molecule, May Lead To New Diabetes, Cancer Drugs
Scientists have solved the structure of a class of proteins known as sodium glucose co-transporters, which pump glucose into cells. The solution of the SGLT structure will accelerate development of new drugs designed to treat patients with diabetes and cancer. The journal Science publishes the findings. (Mon, 07 Jul 2008 18:22:15 GMT)

Curious about Cats?
A UC Davis genomics study of more than 11,000 cats has traced their domestication to the Fertile Crescent. (Mon, 07 Jul 2008 19:10:11 GMT)

SACGHS Task Force Sees Consumer Genomics as 'Number One Priority'
GenomeWeb Daily News You are not logged in. Existing subscribers login here . New to GenomeWeb Daily News? Register quickly here for your free subscription. (Mon, 07 Jul 2008 19:28:28 GMT)

Function of glucose transport molecule clarified
Discovery will accelerate development of new drugs to treat patients with diabetes and cancer. (Mon, 07 Jul 2008 20:39:53 GMT)

posted by Edward H. Trager on Mon 1st Dec 2003 07:38 UTC
I work in a genetics research laboratory at an academic institution. Recently, a colleague of mine was having a lot of trouble with his Windows 2000 workstation. (Mon, 07 Jul 2008 20:49:36 GMT)

Can You Hear Me Now?
When it comes to cellular communication networks, a primitive single-celled microbe that answers to the name of Monosiga brevicollis has a leg up on animals composed of billions of cells. It commands a signaling network more elaborate and diverse than found in any multicellular organism higher up on the evolutionary tree, researchers at the Salk Institute for Biological Studies have discovered. (Mon, 07 Jul 2008 21:22:48 GMT)

Can you hear me now?
When it comes to cellular communication networks, a primitive single-celled microbe that answers to the name of Monosiga brevicollis has a leg up on animals composed of billions of cells. It commands a signaling network more elaborate and diverse than found in any multicellular organism higher up on the evolutionary tree, researchers at the Salk Institute for Biological Studies have discovered. (Mon, 07 Jul 2008 21:49:16 GMT)

Medical Lab Receives Grant for Vaccine Research
Workers at a small lab in Lackawanna County will soon start work on a vaccine to help in case of a bird flu pandemic. A $1.6 million grant was presented to Vital Probes of Mayfield Monday to develop a vaccine in case there is a need to use it. (Mon, 07 Jul 2008 22:10:50 GMT)

Beijing, China July 7, 2008 Chinese Academy of Sciences
botanists have made novel progress on studies of origin and domestication of the Asian cultivated rice Oryza sativa. Their work was published in the June issue of Genetics . (Mon, 07 Jul 2008 23:07:08 GMT)

The Energy Superbugs
Extremophiles create, collect and store power in ways once reserved to the realm of comic book superheroes. Can they teach us how it's done? (Tue, 08 Jul 2008 00:00:27 GMT)

Creating a new approach to archiving human genetic information
A genome sequence is a long sequence written in a four letter code—3 billion letters in the case of a human genome. But what is the meaning—how is the code deciphered? (Tue, 08 Jul 2008 00:08:18 GMT)

How to Check Yourself for Genetic Abnormalities
Curious about that wheat-gluten allergy that runs in the family? Wondering if you're more likely to develop cancer than your mate? There are several options for testing the stuff your genes are made of, ranging from online DNA-sequencing shops to home-brew basement kits. Grab your cotton swabs and confront your future. (Tue, 08 Jul 2008 00:30:52 GMT)

Cell Biosciences appoints key executives
Cell Biosciences, a provider of ultra sensitive protein detection and characterization systems to life science researchers, has appointed Jason Novi as its new CFO. (Tue, 08 Jul 2008 00:31:34 GMT)

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